68700-91-4

Basic information

• Product Name: 2-(6-chloropyridin-3-yl)propan-2-ol
• Synonyms: 2-(6-chloropyridin-3-yl)propan-2-ol
• CAS NO: 68700-91-4
• Molecular Formula: C₈H₁₀ClNO
• Molecular Weight: 171.6241
• Mol File: 68700-91-4.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(6-chloropyridin-3-yl)propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(6-chloropyridin-3-yl)propan-2-ol(68700-91-4)
• EPA Substance Registry System: 2-(6-chloropyridin-3-yl)propan-2-ol(68700-91-4)

Safety Data

• Hazardous Substances Data: 68700-91-4(Hazardous Substances Data)

Usage

Structure

A six-membered heterocyclic ring containing five carbon atoms and one nitrogen atom, with a hydroxyl group attached to the second carbon atom of the propan-2-ol (isopropanol) moiety, and a chlorine atom in the 6-position of the pyridine ring.

Type of compound

A secondary alcohol

Usage

In the synthesis of pharmaceuticals and agrochemicals, commonly used as a building block in organic synthesis for the production of various chemicals and materials.

Upstream product

• 58757-38-3 6-Chloronicotinoyl chloride 
• 917-64-6 methyl magnesium iodide 
• 73781-91-6 6-Chloronicotinic acid methyl ester 
• 75-16-1 methylmagnesium bromide 
• 55676-22-7 3-acetyl-6-chloropyridine 
• 676-58-4 methylmagnesium chloride 
• 53939-30-3 5-bromo-2-chloropyridine 
• 67-64-1 acetone 
• 49608-01-7 6-chloro-3-pyridinecarboxylic acid ethyl ester 

Downstream Products

• 68700-92-5 2-chloro-5-(1-methylethenyl)pyridine 
• 843643-03-8 2-(6-aminopyridin-3-yl)propan-2-ol 
• 1360055-95-3 2-(6-chloropyridin-3-yl)-N-ethylpropan-2-amine 
• 1428527-65-4 N-(2-(6-(4-bromophenyl)pyridin-3-yl)propan-2-yl)acetamide 
• 1428527-64-3 tert-butyl 2-(6-(4-bromophenyl)pyridin-3-yl)propan-2-ylcarbamate 
• 1428527-63-2 diethyl 4-(5-(2-aminopropan-2-yl)pyridin-2-yl)phenylphosphonate 
• 1428527-66-5 4-(5-(2-(4-hydroxy-2-(pyridazin-3-yl)pyrimidine-5-carboxamido)propan-2-yl)pyridine-2-yl)phenylphosphonic acid 
• 1436433-22-5 2-(6-(4-bromophenyl)pyridin-3-yl)propan-2-amine 
• 1436433-27-0 tert-butyl 2-(6-(4-(diethoxyphosphoryl)phenyl)pyridin-3-yl)propan-2-ylcarbamate 
• 1436433-35-0 diethyl 4-(5-(2-(4-hydroxy-2-(pyridazin-3-yl)pyrimidine-5-carboxamido) propan-2-yl)pyridin-2-yl)phenylphosphonate 

Relevant articles and documents

INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS

Provided herein are compounds of formula (V) that bind to BF3 of an androgen receptor (AR), which can modulate the AR for the treatment of Kennedy's disease.

SUBSTITUTED PYRIMIDINES

The present invention relates to substituted pyrimidines useful as HIF prolyl hydroxylase inhibitors to treat anemia and like conditions.

Inhibitors of Bruton's Tyrosine Kinase

This application discloses 6-(2-Hydroxymethyl-phenyl)-2-methyl-2H-pyridazin-3-one derivatives according to generic Formula I: wherein, variables X, R, and Y4, are defined as described herein, which inhibit Btk. The compounds disclosed herein are useful to modulate the activity of Btk and treat diseases associated with excessive Btk activity. The compounds are further useful to treat inflammatory and auto immune diseases associated with aberrant B-cell proliferation, such as rheumatoid arthritis. Also disclosed are compositions containing compounds of Formula I and at least one carrier, diluent or excipient.