69062-86-8

Basic information

• Product Name: 2,4-Dimethyloxazole-5-carboxaldehyde
• Synonyms: 2,4-DIMETHYL-OXAZOLE-5-CARBALDEHYDE;2,4-Dimethyloxazole-5-carboxaldehyde;5-Oxazolecarboxaldehyde, 2,4-dimethyl-;2,4-dimethyl-5-Oxazolecarboxaldehyde
• CAS NO: 69062-86-8
• Molecular Formula: C₆H₇NO₂
• Molecular Weight: 125.13
• Mol File: 69062-86-8.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 207.873°C at 760 mmHg
• Flash Point: 79.519°C
• Appearance: /
• Density: 1.141g/cm³
• Vapor Pressure: 0.22mmHg at 25°C
• Refractive Index: 1.515
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 0.41±0.10(Predicted)
• CAS DataBase Reference: 2,4-Dimethyloxazole-5-carboxaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Dimethyloxazole-5-carboxaldehyde(69062-86-8)
• EPA Substance Registry System: 2,4-Dimethyloxazole-5-carboxaldehyde(69062-86-8)

Safety Data

• Hazardous Substances Data: 69062-86-8(Hazardous Substances Data)

Usage

General Description

2,4-Dimethyloxazole-5-carboxaldehyde is a chemical compound with the molecular formula C6H7NO2. It is a yellow to orange liquid with a melting point of -35°C and a boiling point of 120-122°C. 2,4-Dimethyloxazole-5-carboxaldehyde is used as an intermediate in the synthesis of pharmaceuticals and other organic compounds. It is also a building block for the production of other chemicals and materials. 2,4-Dimethyloxazole-5-carboxaldehyde is primarily used in research and development and industrial applications. It is important to handle this chemical with care and according to safety guidelines, as it can be hazardous if not used properly.

InChI:InChI=1/C6H7NO2/c1-4-6(3-8)9-5(2)7-4/h3H,1-2H3

Upstream product

• 214553-55-6 5-hydroxymethyl-2,4-dimethyloxazole 
• 23012-30-8 2,4-dimethyloxazole-5-ylcarboxylate ethyl ester 

Downstream Products

• 874277-98-2 C₂₇H₃₃N₅O 
• 1599529-59-5 (4-chloro-2-methoxy-3-(4-(trifluoromethyl)benzyl)quinoline-6-yl)(2,4-dimethyloxazol-5-yl)methanol 
• 23012-25-1 2,4-dimethyl-5-acetyloxazole 
• 1616100-75-4 (R)-N-((S)-2-(2,4-difluoro-5-(pyrimidin-5-yl)phenyl)-4-(2,4-dimethyloxazol-5-yl)-4-oxobutan-2-yl)-2-methylpropane-2-sulfinamide 
• 1616100-76-5 (R)-N-((2S,4R)-2-(2,4-difluoro-5-(pyrimidin-5-yl)phenyl)-4-(2,4-dimethyloxazol-5-yl)-4-hydroxybutan-2-yl)-2-methylpropane-2-sulfinamide 
• 1616100-77-6 (1R,3S)-3-amino-3-(2,4-difluoro-5-(pyrimidin-5-yl)phenyl)-1-(2,4-dimethyloxazol-5-yl)butan-1-ol 
• 1616100-78-7 N-(((2S,4R)-2-(2,4-difluoro-5-(pyrimidin-5-yl)phenyl)-4-(2,4-dimethyloxazol-5-yl)-4-hydroxybutan-2-yl)carbamothioyl)benzamide 
• 1616100-26-5 (4S,6S)-4-(2,4-difluoro-5-(pyrimidin-5-yl)phenyl)-6-(2,4-dimethylisoxazol-5-yl)-4-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine 

Relevant articles and documents

Synthesis of oxazolyl- and furanyl-substituted imidazole hydrochlorides and methiodides

Oxazolyl-5- and furanyl-2-substituted imidazoles have been synthesized by coupling the two ring systems via the dipolar cycloadditon of tosyl methyl isocyanide to the corresponding oxazolyl and furanyl aldimines in basic media. These substitute oxazolyl and furanylimidazole bases obtained in this manner were then subjected to hydrogen chloride gas and to methyl iodide to form the corresponding hydrochlorides and methyliodides, respectively. All compounds were purified, characterized and then tested for muscarinic binding affinity. Biological test results revealed low muscarinic receptor affinity and selectivity.