6921-64-8Relevant articles and documents
Eupatriol, a new monoterpene from Eupatorium tashiroi HAYATA
Wu,Niwa,Furukawa,Kuoh
, p. 4005 - 4006 (1985)
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Bioactivity study of thiophene and pyrazole containing heterocycles
Athare, Anil E.,Dare, Sushama B.,Kale, Nitin V.,Karale, Bhausaheb K.,Mhaske, Sadhana D.,Salve, Supriya P.,Takate, Sushama J.
, p. 891 - 899 (2021/09/08)
Chalcones 3a-f were prepared by reacting thiophene containing pyrazolyl aldehyde (2) with different 2-hydroxy acetophenones 1a-f. The compounds 3a-f were transformed into different Pyrazolines 4a-f. The formation of chromene derivatives 5a-f occurred from the cyclization of 3a-f, which were then transformed into pyrazole derivatives 6a-f. Newly synthesized compounds have promising antibacterial activity against S. typhii and S. aureus, while weak activity against B. subtilis and E. coli. Compounds 5d and 6d had significant antifungal action towards A. niger, while most of the compounds were moderately active towards T. viride. Some of the synthesized compounds showed promising α-amylase inhibitory activity at 1 mg/mL concentration.
Synthesis of natural product inulavosin via Ga(OTf)3-Catalyzed Hetero Diels–Alder Dimerization of salicyl alcohol derivative
Gong, Pi-Xian,Li, Hui-Jing,Wang, Meirong,Cheng, Yun-Fei,Wu, Yan-Chao
supporting information, p. 2911 - 2916 (2018/10/15)
Inulavosin, a natural melanogenesis inhibitor, has been synthesized smoothly from readily available and inexpensive starting materials by using a Ga(OTf)3-catalyzed room temperature hetero Diels–Alder dimerization of salicyl alcohol derivative and a regioselective phenol monobromination as the key steps.