6940-47-2

Basic information

• Product Name: CHLOROAC-DL-NVA-OH
• Synonyms: CLAC-DL-NVA-OH;CHLOROAC-DL-NVA-OH;CHLOROACETYL-DL-NORVALINE;N-(chloroacetyl)-DL-norvaline;(±)-N-(chloroacetyl)norvaline;Einecs 230-083-0
• CAS NO: 6940-47-2
• Molecular Formula: C₇H₁₂ClNO₃
• Molecular Weight: 193.63
• EINECS: 230-083-0
• Mol File: 6940-47-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 403.7 °C at 760 mmHg
• Flash Point: 197.9 °C
• Appearance: /
• Density: 1.237 g/cm³
• Vapor Pressure: 1.2E-07mmHg at 25°C
• Refractive Index: 1.48
• CAS DataBase Reference: CHLOROAC-DL-NVA-OH(CAS DataBase Reference)
• NIST Chemistry Reference: CHLOROAC-DL-NVA-OH(6940-47-2)
• EPA Substance Registry System: CHLOROAC-DL-NVA-OH(6940-47-2)

Safety Data

• Hazardous Substances Data: 6940-47-2(Hazardous Substances Data)

Usage

General Description

CHLOROAC-DL-NVA-OH is most likely an abbreviated term for a specific chemical compound. However, no information pertaining to the accurate identity, structure, or properties of a specific compound referred to as "CHLOROAC-DL-NVA-OH" can be found in common chemical databases or scholarly literature. The name suggests it might be related to chloroacetate or NVA (which could refer to N-vinylacetamide), but without further clarification or context, it's impossible to provide an accurate summary. The "-OH" could potentially indicate the presence of a hydroxyl group in the compound. In summary, "CHLOROAC-DL-NVA-OH" is not a well-defined or recognized chemical compound as per existing scientific sources.

InChI:InChI=1/C7H12ClNO3/c1-2-3-5(7(11)12)9-6(10)4-8/h5H,2-4H2,1H3,(H,9,10)(H,11,12)/t5-/m0/s1

Upstream product

• 760-78-1 2-aminopentanoic acid 
• 79-04-9 chloroacetyl chloride 

Downstream Products

• 6600-40-4 L-Norvaline 
• 19476-91-6 2-[2-(Diethoxy-thiophosphorylsulfanyl)-acetylamino]-pentanoic acid 
• 910886-24-7 N-Chloroacetyl D-norvaline 
• 2013-12-9 D-norvaline 
• 34337-03-6 N-chloroacetyl-L-norvaline 

Relevant articles and documents

Kinetic Resolution of Unnatural and Rarely Occuring Amino Acids: Enantioselective Hydrolysis of N-Acyl Amino Acids Catalyzed by Acylase I

Acylase I (aminoacylase; N-acylamino-acid amidohydrolase, EC 3.5.1.14, from porcine kidney and the fungus Aspergillus) is broadly applicable enzymatic catalyst for the kinetic resolution of unnatural and rarely occuring α-amino acids.Its enantioselectivity for the hydrolysis of N-acyl L-α-amino acids is nearly absolute, yet it accepts substrates having a wide range of structure and functionality.This paper reports the initial rates of enzyme-catalyzed hydrolysis of over 50 N-acyl amino acids and analogues, the stabilities of the enzymes in aqueous and aqueous/organic solutions, and the effects of different acyl groups and metal ions on the rates of enzymatic hydrolysis.Eleven α-amino and α-methyl α-amino acids were resolved on a 2-29-g scale.Crude L- and D-amino acid products had generally >90percent ee.The utility of resolved amino acids as chiral synthons was illustrated by the preparation of (R)- and (S)-1-butene oxide and the diastereoselective (cis:trans, 7-8:1) iodolactonization of three 2-amino-4-alkenoic acid derivatives.