6943-65-3

Basic information

• Product Name: ETHYLENEBIS(ISOTHIOURONIUM BROMIDE)
• Synonyms: 2,2’-ethylenebis(2-thio-pseudouredihydrobromide;2,2-ethylenedithiodi-pseudouredihydrobromide;carbamimidothioicacid,1,2-ethanediylester,dihydrobromide;ethylenediisothioureadihydrobromide;ethylenediisothiouroniumdibromide;ETHYLENEBIS(ISOTHIOUREA) DIHYDROBROMIDE;ETHYLENEBIS(ISOTHIOURONIUM BROMIDE);2-([AMINO(IMINO)METHYL]THIO)ETHYL IMIDOTHIOCARBAMATE DIHYDROBROMIDE
• CAS NO: 6943-65-3
• Molecular Formula: 2BrH*C₄H₁₀N₄S₂
• Molecular Weight: 340.1
• EINECS: 230-101-7
• Mol File: 6943-65-3.mol
• Article Data: 9

Chemical Properties

• Melting Point: 229-234 °C(lit.)
• Boiling Point: 326.2°C at 760 mmHg
• Flash Point: 151.1°C
• Appearance: /
• Density: 1.57g/cm³
• Vapor Pressure: 0.000219mmHg at 25°C
• Refractive Index: 1.712
• Sensitive: Hygroscopic
• BRN: 3914616
• CAS DataBase Reference: ETHYLENEBIS(ISOTHIOURONIUM BROMIDE)(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYLENEBIS(ISOTHIOURONIUM BROMIDE)(6943-65-3)
• EPA Substance Registry System: ETHYLENEBIS(ISOTHIOURONIUM BROMIDE)(6943-65-3)

Safety Data

• Statements: 22
• Safety Statements: 22-36/37
• RIDADR: 2811
• WGK Germany: 3
• RTECS: UM6790000
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 6943-65-3(Hazardous Substances Data)

Usage

General Description

ETHYLENEBIS(ISOTHIOURONIUM BROMIDE) is a chemical compound commonly used as a biocide and preservative in industrial water treatment systems. It is an effective antimicrobial agent, particularly against bacteria, algae, and fungi, and is often used to control and prevent the growth of these microorganisms in cooling towers, process water, and other industrial systems. The compound works by disrupting the cell membranes of the target microorganisms, leading to their destruction. It is typically applied in liquid form and is known for its stability and long-lasting antimicrobial effects, making it a popular choice for controlling microbial growth in various industrial applications. However, it is important to use this chemical with caution and adhere to safety guidelines to minimize potential health and environmental risks.

InChI:InChI=1/C4H10N4S2/c5-3(6)9-1-2-10-4(7)8/h1-2H2,(H3,5,6)(H3,7,8)

Upstream product

• 106-93-4 ethylene dibromide 
• 17356-08-0 thiourea 
• 80410-54-4 S-2-bromoethylisothiourea hydrobromide 

Downstream Products

• 7244-02-2 (ethylenedithio)diacetic acid 
• 629-17-4 1,2-bis(thiocyanato)ethane 
• 100-32-3 di(p-nitrophenyl) disulfide 
• 1223-31-0 bis(4-nitrophenyl)sulfide 
• 71532-93-9 1,2-bis(4-nitrophenylthio) ethane 
• 296-40-2 7,16-dioxa-1,4,10,13-tetrathiacyclooctadecane 
• 40254-01-1 1,4-dioxa-7,10-dithiacyclododecane 
• 3570-55-6 3-thiapentan-1,5-dithiol 
• 540-63-6 ethane-1,2-dithiol 

Relevant articles and documents

The 1,4-dithiin ring opening in 1,4-dithiinodiquinolines as a route to quinoline crown thioethers

Quinoline crown thioethers (7) and (8) with 8-, 9-, 10-, 11-, 12-, 18-, 20-, 21- and 24-membered macrocyclic thiacrown ring were obtained by the 1,4- dithiin ring opening in 1,4-dithiinodiquinolines (1) and (2) with divalent sulfur nucleophiles followed by S-alkylation with divalent alkylating agents. Thiacrowns (7) and (8) contain two or four quinoline units.

EFFECT OF VICINAL SUBSTITUENTS ON REACTIVITY IN BIMOLECULAR NUCLEOPHILIC SUBSTITUTION AT A SATURATED CARBON ATOM. TWO TYPES OF SUBSTITUENT I. KINETICS OF THE REACTIONS OF THIOUREA WITH β-SUBSTITUTED BROMOETHANES IN DIMETHYLFORMAMIDE

The kinetics of the reaction of thiourea with β-substituted bromoethanes in DMFA were studied by radiochromatography.It was shown that there is no isokinetic relationship or Taft equation for all the substituents but that there are isokinetic relationships for two separate reaction series, one of which is described satisfactorily by a Taft equation taking account of the inductive and steric effects of the substituents.On the basis of the obtained data it is supposed that there are two types of vicinal substituents, which affect the reactivity of the bromine at the saturated carbon atom by different mechanisms.For the first type of substituent (H, F, Br, CH3, C6H5) the main factors determining the reactivity are the inductive and steric effects of the substituents.Substituents of the second type (COOH, COOC2H5, CN, NH3Br, SC(NH2)2Br) include charged or highly polar substituents, and this makes it possible to expect a field effect, leading to additional stabilization of the transition state.

ORGANIC SYNTHESIS USING PTC-5: NUCLEOPHILIC AROMATIC SUBSTITUTION UNDER LIQUID-LIQUID AND SOLID-LIQUID PHASE TRANSFER CONDITIONS.

The reaction of 1-chloro-4-nitrobenzene (1) with dithiols generated in situ from thiouronium salts (2) under PT conditions, which in turn have been procured by the reaction of appropriate α,ω-dibromoalkanes with thiourea have been investigated.The reactions of (1) with various diols have also been investigated and their reaction mechanism is discussed.