694471-97-1

Basic information

• Product Name: (4-(3-PYRIDYLOXY)PHENYL)SULFONYL CHLORIDE HYDROCHLORIDE
• Synonyms: 4-(PYRIDIN-3-YLOXY)BENZENESULFONYL CHLORIDE HYDROCHLORIDE;(4-(3-PYRIDYLOXY)PHENYL)SULFONYL CHLORIDE HYDROCHLORIDE;4-(3-PYRIDYLOXY)PHENYLSULPHONYL CHLORIDE HYDROCHLORIDE;4-(3-Pyridyloxy)Benzenesulfonyl Chloride Hydrochloride;4-(Pyridin-3-yloxy)benzene-1-sulfonylchloride hydrochloride;4-(Pyridin-3-yloxy)benzene-1-sulfonyl chloride
• CAS NO: 694471-97-1
• Molecular Formula: C₁₁H₈ClNO₃S
• Molecular Weight: 306.17
• Mol File: 694471-97-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 392.1 °C at 760 mmHg
• Flash Point: 191 °C
• Appearance: /
• Density: 1.42 g/cm³
• Vapor Pressure: 2.03E-07mmHg at 25°C
• CAS DataBase Reference: (4-(3-PYRIDYLOXY)PHENYL)SULFONYL CHLORIDE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (4-(3-PYRIDYLOXY)PHENYL)SULFONYL CHLORIDE HYDROCHLORIDE(694471-97-1)
• EPA Substance Registry System: (4-(3-PYRIDYLOXY)PHENYL)SULFONYL CHLORIDE HYDROCHLORIDE(694471-97-1)

Safety Data

• Hazard Codes: C
• RIDADR: UN1759
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 694471-97-1(Hazardous Substances Data)

Usage

General Description

The chemical (4-(3-Pyridyloxy)phenyl)sulfonyl chloride hydrochloride is a compound that consists of a sulfonyl chloride group attached to a phenyl ring that is substituted with a pyridyloxy group. It is commonly used as a reagent in organic synthesis for the introduction of sulfonyl chloride groups into organic molecules. Sulfonyl chlorides are often used as protecting groups in organic chemistry, as well as in the synthesis of pharmaceuticals and agrochemicals. The addition of the hydrochloride group in this compound makes it more soluble in water, which can be advantageous for certain reactions or applications. Overall, (4-(3-Pyridyloxy)phenyl)sulfonyl chloride hydrochloride is an important chemical reagent with various uses in organic synthesis and chemical research.

InChI:InChI=1/C11H8ClNO3S.ClH/c12-17(14,15)11-5-3-9(4-6-11)16-10-2-1-7-13-8-10;/h1-8H;1H

Upstream product

• 2176-45-6 3-phenoxypyridine 
• 1000340-09-9 C₁₁H₉NO₄S 

Relevant articles and documents

COMPOUNDS WITH PGD2 ANTAGONIST ACTIVITY

Compounds of general formula (I); wherein R1, R2, R3 and R4 are independently hydrogen, halo, -C1-C6 alkyl, -O(C1-C6 alkyl), -C1-C6 alkyl(C3-C7 cycloalkyl), -CON(R9)2, -SOR9, -S02R9, -S02N(R9)2, -N(R9)2, -NR9OR9, -C02R9, COR9, -SR9, -OH, -N02 or -CN; each R9 independently hydrogen or C1-C6 alkyl, R5 and R6 are each independently hydrogen, or C1-C6 alkyl or together with the carbon atom to which they are attached form a C3-C7 cycloalkyl group; R7 is hydrogen or C1-C6 alkyl; R8 is C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl or an aromatic moiety, any of which may optionally be substituted with one or more substituents selected from halo, -SOR13 -S02R13, -R14, -OR14, -CON(R14)2 -SOR14, -S02R14, -S02N(R14) -S02N(R14)2, -N(R 14)2, NR14COR14, -CO2R14, COR14, -SR14, -N02 or -CN; wherein R13 is a 5 to 7 membered heterocyclic ring, and each R14 is independently hydrogen, alkyl or aryl, the aryl being optionally substituted by -R9, -OR9, -CON(R9)2, -SOR9 -S02R9, -S02N(R9)2, -N(R9)2, NR9COR9, -C02R9, -COR9, -SR9, halo, -N02 or -CN, wherein R9 is as defined above; provided that when R1, R3 and R4 are hydrogen and R2 is hydrogen, halogen or -0(C1-C6)alkyl, R8 is not unsubstituted phenyl or phenyl substituted by halo, C1-C6 alkyl, -0(C1-C6)alkyl, -S(C1-C6)alkyl or -CO(C1-C6)alkyl, or pharmaceutically acceptable salts, hydrates, solvates, complexes or prodrugs therof are useful in the treatment of allergic diseases such as asthma, allergic rhinitis and atopic dermatitis