69457-08-5Relevant articles and documents
Synthesis of new 1-(3,4-dimethylphenyl)-1,5-dihydropyrazolo[3,4-d]pyrimidin-4-one derivatives
Zhidkov,Kutkin,Fetisova,Zverev,Zaraeva,Gorokhov,Chubarova
, p. 592 - 598 (2017/06/06)
New substituted pyrazolo[3,4-d]pyrimidin-4-ones have been synthesized as a result of a series of transformations including hydrolysis of ethyl 5-amino-1H-pyrazole-4-carboxylates, cyclization of the carboxylic acids thus obtained to pyrazolo[3,4-d][1,3]oxazin-4(1H)-ones, and treatment of the latter with substituted anilines. The final pyrazolo[3,4-d]pyrimidin-4-one derivatives can also be synthesized from 5-(arylamido)-1H-pyrazole-4-carboxylic acids in the presence of a catalytic amount of anhydrous zinc(II) chloride.
Synthesis and Pharmacology of Some New Oxime Ethers Derived from 2-Acetyl-5-arylthiophenes
Shridhar, D. R.,Sastry, C. V. Reddy,Chaturvedi, S. C.,Gurumurthy, R.,Singh, P. P.,et al.
, p. 692 - 694 (2007/10/02)
Several new 5-arylthiophene-2-acetoxime ethers (1-28) have been synthesised and screened for their pharmacological activities.Some of these compounds possess moderate antiinflammatory and mild CNS depressant activities.The intermediate 2-acetyl-5-(p-ethyl/p-iso-propyl/3,4-dimethylphenyl)thiophenes (1b-d) and their oximes (IIb-d) have been reported for the first time.