69491-52-7Relevant articles and documents
Meta-Selective CAr-H Nitration of Arenes through a Ru3(CO)12-Catalyzed Ortho-Metalation Strategy
Fan, Zhoulong,Ni, Jiabin,Zhang, Ao
supporting information, p. 8470 - 8475 (2016/07/26)
The first example of transition metal-catalyzed meta-selective CAr-H nitration of arenes is described. With the use of Ru3(CO)12 as the catalyst and Cu(NO3)2·3H2O as the nitro source, a wide spectrum of arenes bearing diversified N-heterocycles or oximido as the directing groups were nitrated with meta-selectivity exclusively. Mechanism studies have demonstrated the formation of a new 18e-octahedral ruthenium species as a key ortho-CAr-H metalated intermediate, which may be responsible for the subsequent meta-selective electrophilic aromatic substitution (SEAr). Moreover, this approach provides a fast-track strategy for atom/step economical synthesis of many useful pharmaceutical molecules.
Scope of the inverse electron demand Diels-Alder reactions of 1,2,3-triazine
Anderson, Erin D.,Boger, Dale L.
supporting information; experimental part, p. 2492 - 2494 (2011/07/09)
Chemical equations presented. An examination of the scope of the inverse electron demand Diels-Alder reactions of the parent unsubstituted 1,2,3-triazine is described including the first report of its unique capabilities for participating in previously unexplored [4 + 2] cycloaddition reactions with heterodienophiles.
Palladium-Catalyzed Regioselective C-H Bond ortho-Acetoxylation of Arylpyrimidines
Zheng, Xiaojian,Song, Bingrui,Xu, Bin
supporting information; experimental part, p. 4376 - 4380 (2010/10/04)
An efficient and regioselective palladium-catalyzed ortho C-H acetoxylation reaction was developed to afford, ortho monoacetoxylated arylpyrimidmes in good to excellent yields by using cupric trifluoroacetate as a cocatalyst. A wide variety of oxygenated
