6954-69-4

Basic information

• Product Name: 2,5-DIMETHYL-4-NITRO ACETANILIDE
• Synonyms: 2,5-DIMETHYL-4-NITRO ACETANILIDE;N-(2,5-Dimethyl-4-nitrophenyl)acetamide;Nsc67711;4'-Nitro-2',5'-acetoxylidide
• CAS NO: 6954-69-4
• Molecular Formula: C₁₀H₁₂N₂O₃
• Molecular Weight: 208.21
• Mol File: 6954-69-4.mol
• Article Data: 7

Chemical Properties

• Melting Point: 171-171.5℃ (benzene chloroform )
• Boiling Point: 381.2 °C at 760 mmHg
• Flash Point: 184.4 °C
• Appearance: /
• Density: 1.247 g/cm³
• Vapor Pressure: 5.15E-06mmHg at 25°C
• Refractive Index: 1.595
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2,5-DIMETHYL-4-NITRO ACETANILIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-DIMETHYL-4-NITRO ACETANILIDE(6954-69-4)
• EPA Substance Registry System: 2,5-DIMETHYL-4-NITRO ACETANILIDE(6954-69-4)

Safety Data

• Hazardous Substances Data: 6954-69-4(Hazardous Substances Data)

Usage

General Description

2,5-DIMETHYL-4-NITRO ACETANILIDE is a chemical compound also known as Diclofenac, a nonsteroidal anti-inflammatory drug (NSAID). It is commonly used to treat pain, inflammation, and fever in conditions such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. The compound works by inhibiting the production of certain chemicals in the body that cause inflammation and pain. It is often administered orally in the form of tablets or capsules, and is available by prescription in various strengths. However, it can also be found in topical forms such as gels and patches for localized pain relief. While generally well-tolerated, potential side effects may include stomach irritation, dizziness, and headache.

InChI:InChI=1/C10H12N2O3/c1-6-5-10(12(14)15)7(2)4-9(6)11-8(3)13/h4-5H,1-3H3,(H,11,13)

Upstream product

• 2050-44-4 N-(2,5-dimethylphenyl)acetamide 
• 7697-37-2 nitric acid 
• 95-78-3 2,5-Dimethylaniline 
• 75-36-5 acetyl chloride 
• 3460-29-5 4-nitro-2,5-xylidine 

Downstream Products

• 3460-29-5 4-nitro-2,5-xylidine 
• 857616-55-8 acetic acid-(2,5-dimethyl-4-nitro-N-nitroso-anilide) 
• 6393-01-7 2,5-Dimethyl-1,4-phenylenediamine 
• 81115-43-7 6-methyl-5-nitro-1H-indazole 
• 81115-45-9 6-methyl-1H-indazole-5-amine 
• 106423-99-8 2,2′,5,5′-tetramethyl-4,4′-azodiacetanilide 
• 23410-20-0 2,5-dimethyl-4-aminoacetanilide 
• 15540-81-5 1-bromo-2,5-dimethyl-4-nitrobenzene 

Relevant articles and documents

FORMIMIDAMIDINE COMPOUNDS USEFUL AGAINST PHYTOPATHOGENIC MICROORGANISMS

The present invention relates to 4-substituted amidine derivatives of the general formula (I), wherein A1-A4, D, L, Q, R7, R7' and integer's v and w have the meanings as defined in description. The invention further relates to methods for their preparation and use of said compounds to fight undesired phytopathogenic microorganisms, and agents for said purpose, comprising said amidine derivatives, all according to the invention. This invention further relates to a method for controlling undesired phytopathogenic microorganisms by application of said 4-substituted amidine derivatives of general formula (I) to such undesired microorganisms and/or to their habitat, according to the invention. (I)

5-ALKYL/ALKENYL-3-CYANOPYRIDINES AS KINASE INHIBITORS

Described herein are compounds of formula I: wherein G is and pharmaceutically acceptable salts thereof, wherein J, X, R1, R2, R11, R12' and p are as defined herein. Also provided herein are methods of making the compounds of formula I, and methods of using these compounds for inhibiting or treating a pathological condition or disorder linked to or mediated by a protein kinase in a mammal.

Ozone-mediated Reaction of Anilides and Phenyl Esters with Nitrogen Dioxide: Enhanced Ortho-reactivity and Mechanistic Implications

In the presence of ozone, anilides 1 can be nitrated rapidly with nitrogen dioxide in chloroform at 0 deg C to give a high proportion of ortho-nitro derivatives (ortho:para = 1.2-4.4) in good yields.The phenyl esters 15 can be similarly nitrated on the aromatic ring without significant cleavage of the ester bond, giving a mixture of isomeric nitro derivatives in which the ortho-isomer predominantes (ortho:para = 1.1-1.5).The oridin of the enhanced ortho reactivity is discussed in terms of an electron-transfer process involving the nitrogen trioxide as initial electrophile.