6958-31-2

Basic information

• Product Name: 1,3-Propanediamine,N1,N3-bis[(4-methoxyphenyl)methylene]-
• Synonyms: 1,3-Propanediamine,N,N'-bis(p-methoxybenzylidene)- (7CI,8CI); 1,3-Propanediamine,N,N'-bis[(4-methoxyphenyl)methylene]- (9CI); NSC 64661
• CAS NO: 6958-31-2
• Molecular Formula: C19H22 N2 O2
• Molecular Weight: 310.396
• Mol File: 6958-31-2.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 458.4°Cat760mmHg
• Flash Point: 185.5°C
• Density: 1.02g/cm³
• CAS DataBase Reference: 1,3-Propanediamine,N1,N3-bis[(4-methoxyphenyl)methylene]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Propanediamine,N1,N3-bis[(4-methoxyphenyl)methylene]-(6958-31-2)
• EPA Substance Registry System: 1,3-Propanediamine,N1,N3-bis[(4-methoxyphenyl)methylene]-(6958-31-2)

Safety Data

• Hazardous Substances Data: 6958-31-2(Hazardous Substances Data)

Usage

Description

1,3-Propanediamine,N1,N3-bis[(4-methoxyphenyl)methylene]-, also known as bis(4-methoxybenzylidene)propane-1,3-diamine, is a chemical compound characterized by its molecular formula C18H22N2O2. This diamine derivative features two 4-methoxybenzylidene groups attached to the nitrogen atoms, endowing it with unique chemical properties and potential applications in medicine and materials science. Its ability to bind to certain biological targets makes it a compound of interest for various applications. However, due to potential hazards to human health and the environment, it is crucial to handle this compound with care and store it under controlled conditions.

Uses

Used in Pharmaceutical Industry:
1,3-Propanediamine,N1,N3-bis[(4-methoxyphenyl)methylene]is used as a pharmaceutical intermediate for the synthesis of various drugs. Its unique chemical structure allows it to bind to specific biological targets, making it a valuable component in the development of new therapeutic agents.
Used in Materials Science:
In the field of materials science, 1,3-Propanediamine,N1,N3-bis[(4-methoxyphenyl)methylene]is utilized as a building block for the creation of novel materials with specific properties. Its ability to form stable complexes with other molecules contributes to the development of advanced materials with potential applications in various industries.
Used in Chemical Research:
1,3-Propanediamine,N1,N3-bis[(4-methoxyphenyl)methylene]serves as a subject of chemical research, where its unique properties and reactivity are studied to gain insights into new chemical reactions and mechanisms. This research can lead to the discovery of new compounds and applications in various fields.

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 109-76-2 Trimethylenediamine 

Downstream Products

• 6968-78-1 1,3-bis-(4-methoxy-benzyl)-2-(4-nitro-phenyl)-hexahydro-pyrimidine 
• 96074-99-6 2-[1,3-bis-(4-methoxy-benzyl)-hexahydro-pyrimidin-2-yl]-phenol 
• 96174-62-8 1,3-bis-(4-methoxy-benzyl)-2-(4-methoxy-phenyl)-hexahydro-pyrimidine 
• 96764-88-4 1,3-bis-(4-methoxy-benzyl)-2-phenyl-hexahydro-pyrimidine 
• 97013-79-1 4-(1,3-bis(4-methoxybenzyl)hexahydropyrimidin-2-yl)-N,N-dimethylaniline 
• 447410-14-2 1,3-bis(4-methoxybenzyl)-2-(pyridin-4-yl)hexahydropyrimidine 
• 211058-22-9 [((E)-3-{[1-(Diphenoxy-phosphoryl)-1-(4-methoxy-phenyl)-meth-(Z)-ylidene]-amino}-propylimino)-(4-methoxy-phenyl)-methyl]-phosphonic acid diphenyl ester 
• 59211-76-6 N⁽¹⁾,N⁽³⁾-3-bis(4-methoxybenzyl)propane-1,3-diamine 
• 91122-54-2 C₂₃H₂₆N₂O₄S₂ 

Relevant articles and documents

Molybdenum-catalyzed diastereoselective anti-dihydroxylation of secondary allylic alcohols

In this protocol, we report a Mo-catalyzed anti-dihydroxylation of secondary allylic alcohols, providing a general method for the preparation of 1,2,3-triols bearing up to three continuous stereocenters with excellent diastereocontrol. The mechanistic studies reveal that this dihydroxylation reaction consists of two steps and up to excellent diastereomeric ratios of the final triol products can be achieved due to the high level of both diastereocontrol in the initial epoxidation and regiocontrol in the following hydrolysis in situ.

Synthesis and in vitro antioxidant evaluation of new bis(α-aminoalkyl)phosphinic acid derivatives

Diamines were added to arylaldehydes in ethanol, which resulted in corresponding diimines. Novel bis-1-aminophosphinic acid compounds were synthesized through the interaction of diimines and hypophosphorous acid. The new compounds were characterized by elemental analyses, FT-IR and1H,13C and31P NMR techniques. The in vitro antioxidant activity of the newly synthesized compounds were measured and found to exhibit significantly higher antioxidant activity than the standard.

Synthesis and evaluation of hexahydropyrimidines and diamines as novel hepatitis C virus inhibitors

In order to identify novel anti-hepatitis C virus (HCV) agents we devised cell-based strategies and screened phenotypically small molecule chemical libraries with infectious HCV particles, and identified a hit compound (1) containing a hexahydropyrimidine (HHP) core. During our cell-based SAR study, we observed a conversion of HHP 1 into a linear diamine (6), which is the active component in inhibiting HCV and exhibited comparable antiviral activity to the cyclic HHP 1. In addition, we engaged into the biological characterization of HHP and demonstrated that HHP does not interfere with HCV RNA replication, but with entry and release of viral particles. Here we report the results of the preliminary SAR and mechanism of action studies with HHP.