696-30-0 Usage
Description
4-Isopropylpyridine is an organic compound that belongs to the pyridine family, characterized by the presence of an isopropyl group attached to the 4th position of the pyridine ring. It is a liquid at room temperature and exhibits good solubility in various solvents.
Uses
Used in Chemical Synthesis:
4-Isopropylpyridine is used as a reagent in the synthesis of Bis(alkylpyridinium) compounds, which possess antifungal and cytotoxic properties. These compounds have potential applications in the pharmaceutical industry for the development of new drugs targeting fungal infections and certain types of cancer.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-Isopropylpyridine is used as a building block for the development of various active pharmaceutical ingredients (APIs). Its unique chemical structure allows for the creation of novel molecules with specific biological activities, contributing to the discovery of new drugs for various therapeutic areas.
Used in Material Science:
4-Isopropylpyridine can also be utilized in the field of material science, particularly in the design and synthesis of new materials with tailored properties. Its ability to form stable complexes with various metal ions makes it a promising candidate for the development of advanced materials with applications in catalysis, sensors, and energy storage devices.
Used in Analytical Chemistry:
Due to its unique chemical properties, 4-Isopropylpyridine can be employed as a chiral selector in analytical chemistry for the separation and analysis of enantiomers. This application is particularly relevant in the pharmaceutical industry, where the enantiomeric purity of chiral drugs is crucial for ensuring their safety and efficacy.
Check Digit Verification of cas no
The CAS Registry Mumber 696-30-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,9 and 6 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 696-30:
(5*6)+(4*9)+(3*6)+(2*3)+(1*0)=90
90 % 10 = 0
So 696-30-0 is a valid CAS Registry Number.
InChI:InChI=1/C8H11N/c1-7(2)8-3-5-9-6-4-8/h3-7H,1-2H3
696-30-0Relevant articles and documents
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Inubushi et al.
, p. 2007,2023 (1964)
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Practical and Regioselective Synthesis of C-4-Alkylated Pyridines
Baran, Phil S.,Choi, Jin,Godineau, Edouard,Laudadio, Gabriele
, p. 11927 - 11933 (2021/08/20)
The direct position-selective C-4 alkylation of pyridines has been a long-standing challenge in heterocyclic chemistry, particularly from pyridine itself. Historically this has been addressed using prefunctionalized materials to avoid overalkylation and mixtures of regioisomers. This study reports the invention of a simple maleate-derived blocking group for pyridines that enables exquisite control for Minisci-type decarboxylative alkylation at C-4 that allows for inexpensive access to these valuable building blocks. The method is employed on a variety of different pyridines and carboxylic acid alkyl donors, is operationally simple and scalable, and is applied to access known structures in a rapid and inexpensive fashion. Finally, this work points to an interesting strategic departure for the use of Minisci chemistry at the earliest possible stage (native pyridine) rather than current dogma that almost exclusively employs Minisci chemistry as a late-stage functionalization technique.
Heterogeneously palladium-catalyzed acceptorless dehydrogenative aromatization of cyclic amines
Oyama, Takashi,Yatabe, Takafumi,Jin, Xiongjie,Mizuno, Noritaka,Yamaguchi, Kazuya
supporting information, p. 517 - 520 (2019/06/11)
In this manuscript, we report an efficient heterogeneously catalyzed acceptorless dehydrogenative aromatization of cyclic amines under relatively mild conditions. In the presence of a supported catalyst Pd/LDH (LDH = layered double hydroxide), various kinds of structurally diverse cyclic amines including piperidines, tetrahydro(iso)quinolines, and indolines could be converted into the corresponding heteroarenes. Pd/LDH could be reused several times though its catalytic activity gradually declined due to the increase in the palladium particle size.