69624-11-9Relevant articles and documents
MALT1 INHIBITORS AND USES THEREOF
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Page/Page column 51-52, (2021/10/15)
The invention provides compounds of formula (I) wherein R1, R2, R3, R4 and R5 are as defined in the specification which are potent inhibitors of the enzyme MALT1 and are useful in the treatment of autoimmune disorders and diseases and as an immunooncology approach to the treatment of cancer, especially bladder cancer, colon cancer, hepatocellular cancer and small cell or non-small cell lung cancer.
Acid Catalyzed Chlorination of Pyrrole With N-Chloroacetanilide
Rosa, Michael De
, p. 1585 (2007/10/02)
The chlorination of pyrrole with N-chloroacetanilide was catalyzed by acetic acid.Transfer of Cl+ occurred directly to the α and β positions of pyrrole and a mixture of 2-chloro-, 3-chloro- and 2,5-dichloropyrrole was formed.The α/β ratio was 10:1 under competitive conditions.