69689-81-2

Basic information

• Product Name: (E)-α-[(TriphenylMethoxy)iMino]-2-[(triphenylMethyl)aMino]-4-thiazoleacetic Acid
• Synonyms: (E)-2-(TrityloxyiMino)-2-[2-(tritylaMino)thiazol-4-yl]acetic Acid;(E)-α-[(TriphenylMethoxy)iMino]-2-[(triphenylMethyl)aMino]-4-thiazoleacetic Acid
• CAS NO: 69689-81-2
• Molecular Formula: C₄₃H₃₃N₃O₃S
• Molecular Weight: 671.80542
• Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & Selenium Compounds
• Mol File: 69689-81-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 832.8±75.0 °C(Predicted)
• Appearance: /
• Density: 1.19±0.1 g/cm3(Predicted)
• Solubility: Dimethyl Formamide, Dimethyl Sulfoxide
• PKA: 2.38±0.41(Predicted)
• CAS DataBase Reference: (E)-α-[(TriphenylMethoxy)iMino]-2-[(triphenylMethyl)aMino]-4-thiazoleacetic Acid(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-α-[(TriphenylMethoxy)iMino]-2-[(triphenylMethyl)aMino]-4-thiazoleacetic Acid(69689-81-2)
• EPA Substance Registry System: (E)-α-[(TriphenylMethoxy)iMino]-2-[(triphenylMethyl)aMino]-4-thiazoleacetic Acid(69689-81-2)

Safety Data

• Hazardous Substances Data: 69689-81-2(Hazardous Substances Data)

Usage

Chemical Properties

Off-white Solid

Uses

Intermediate in the preparation of (E)-Cefdinir (C242665).

Upstream product

• 64513-00-4 2-(2-amino-4-thiazolyl)-2-(Z)-hydroxyimino-acetic acid ethyl ester 
• 69689-79-8 (2-tritylamino-thiazol-4-yl)-(E)-trityloxyimino-acetic acid ethyl ester 

Downstream Products

• 178601-88-2 7β-[(E)-2-(2-amino-4-thiazolyl)-2-(hydroxyimino)acetamido]-3-vinylcephem-4-carboxylic acid 

Relevant articles and documents

CARBACEPHEM β-LACTAM ANTIBIOTICS

Carbacephem β-lactam antibiotics having the following chemical structures (I) and (II) are disclosed, including stereoisomers, pharmaceutically acceptable salts, esters and prodrugs thereof, wherein Ar2, R1, R2 and R3 are as defined herein. The compounds are useful for the treatment of bacterial infections, in particular those caused by methicillin-resistant Staphylococcus spp.