697754-30-6

Basic information

• Product Name: (3S)-3-(dibenzylamino)-1,1,1-trifluoro-5-methylhexan-2-one
• Synonyms: (3S)-3-(dibenzylamino)-1,1,1-trifluoro-5-methylhexan-2-one
• CAS NO: 697754-30-6
• Molecular Weight: 363.423
• Mol File: 697754-30-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3S)-3-(dibenzylamino)-1,1,1-trifluoro-5-methylhexan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3S)-3-(dibenzylamino)-1,1,1-trifluoro-5-methylhexan-2-one(697754-30-6)
• EPA Substance Registry System: (3S)-3-(dibenzylamino)-1,1,1-trifluoro-5-methylhexan-2-one(697754-30-6)

Safety Data

• Hazardous Substances Data: 697754-30-6(Hazardous Substances Data)

Downstream Products

• 697754-01-1 (+)-(2R,3S)-3-(dibenzylamino)-1,1,1-trifluoro-5-methylhexan-2-ol 
• 697754-10-2 (2R,3S)-3-amino-1,1,1-trifluoro-5-methyl-2-hexanol 

Relevant articles and documents

Diastereoselective synthesis of β-amino-α-(trifluoromethyl) alcohols from homochiral α-dibenzylamino aldehydes

Homochiral α-dibenzylamino aldehydes, prepared from the corresponding α-amino acids, react with trimethyl(trifluoromethyl)silane in THF at 0 °C to afford, in good yields and dr, β-amino-α-(trifluoromethyl) alcohols; anti diastereomers were formed as major products in the trifluoromethylation reaction whereas syn diastereomers were obtained as single isomers in a two-step procedure. Swern oxidation of the mixtures formed in the trifluoromethylation leads to the corresponding α-dibenzylamino trifluoromethyl ketones which undergo diastereoselective reduction with sodium borohydride. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.