69836-64-2 Usage
Description
N-(4-FURAN-2-YL-PHENYL)-ACETAMIDE, also known as furanacetamide, is a chemical compound that belongs to the class of acetamides. It is a white to off-white crystalline powder that is insoluble in water but soluble in organic solvents. N-(4-FURAN-2-YL-PHENYL)-ACETAMIDE is commonly used in the synthesis of pharmaceuticals and agricultural chemicals, as well as in the production of dyes and pigments. Furanacetamide is also known for its potential use as an antioxidant and anti-inflammatory agent. Additionally, it is a known inhibitor of the enzyme catechol-O-methyltransferase (COMT), which plays a role in the metabolism of neurotransmitters.
Uses
Used in Pharmaceutical Industry:
N-(4-FURAN-2-YL-PHENYL)-ACETAMIDE is used as an intermediate in the synthesis of pharmaceuticals for its potential antioxidant and anti-inflammatory properties. It aids in the development of drugs that can target various health conditions.
Used in Agricultural Chemical Industry:
N-(4-FURAN-2-YL-PHENYL)-ACETAMIDE is used as a component in the production of agricultural chemicals, contributing to the development of effective and efficient products for crop protection and enhancement.
Used in Dye and Pigment Industry:
N-(4-FURAN-2-YL-PHENYL)-ACETAMIDE is used as a key compound in the creation of dyes and pigments, providing a wide range of colors and properties for various applications.
Used in Neurotransmitter Metabolism Research:
N-(4-FURAN-2-YL-PHENYL)-ACETAMIDE is used as an inhibitor of the enzyme catechol-O-methyltransferase (COMT) for research purposes, helping scientists understand the role of this enzyme in neurotransmitter metabolism and its implications in various neurological conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 69836-64-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,8,3 and 6 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 69836-64:
(7*6)+(6*9)+(5*8)+(4*3)+(3*6)+(2*6)+(1*4)=182
182 % 10 = 2
So 69836-64-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H11NO2/c1-9(14)13-11-6-4-10(5-7-11)12-3-2-8-15-12/h2-8H,1H3,(H,13,14)
69836-64-2Relevant articles and documents
Scope of the suzuki-Miyaura cross-coupling reactions of potassium heteroaryltrifluoroborates
Molander, Gary A.,Canturk, Belgin,Kennedy, Lauren E.
supporting information; experimental part, p. 973 - 980 (2009/07/11)
A wide variety of bench-stable potassium heteroaryltrifluoroborates were prepared, and general reaction conditions were developed for their cross-coupling to aryl and heteroaryl halides. The cross-coupled products were obtained in good to excellent yields. This method represents an efficient and facile installation of heterocyclic building blocks onto preexisting organic substructures.
ELECTROOXIDATION OF 2-ARYLFURANS
Janda, Miroslav,Srogl, Jan,Dvorakova, Hana,Dvorak, Dalimil,Stibor, Ivan
, p. 906 - 916 (2007/10/02)
Electrochemical methoxylation of 2-phenylfuran (I) and 2-(4-nitrophenyl)furan (VI) proceeded anomalously, affording 5-methoxy-2-phenylfuran (XI) and 5-methoxy-2-(4-nitrophenyl)furan (XIII), respectively. 2-Phenyl-5-methylfuran (II) and methyl-2-(2-methylphenyl)-3-furoate (VIII) behaved normally giving the respective 2,5-dimethoxy-2,5-dihydrofuran derivatives XII and XIV.The suggested ECNECB mechanism of the anomalous methoxylation was confirmed by methoxylation of compound II, in which the methyl group hinders the last CB step, and also of compound VIII in whichthe aromaticity is suppresed by forced deviation from planarity.Forced deviation from planarity was moreover studied also on 2-(4-methylphenyl)furan (III), 5-methyl-2-(2-methylphenyl)furan (IV) and 3,5-dimethyl-2-(2-methylphenyl)furan (V) as model compounds.For all the derivatives the INDO charges were calculated and correlated with the 1H- and 13C-NMR spectra.The experimental electronic spectra were correlated with the theoretical ones (INDO-S-CI).All results obtained confirm the suggested mechanism.
