698387-12-1

Basic information

• Product Name: (E)-1,2-di(quinoline-3-yl)ethene
• CAS NO: 698387-12-1
• Molecular Weight: 282.345
• Mol File: 698387-12-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-1,2-di(quinoline-3-yl)ethene(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1,2-di(quinoline-3-yl)ethene(698387-12-1)
• EPA Substance Registry System: (E)-1,2-di(quinoline-3-yl)ethene(698387-12-1)

Safety Data

• Hazardous Substances Data: 698387-12-1(Hazardous Substances Data)

Upstream product

• 2142-70-3 2-iodoacetophenone 

Relevant articles and documents

One-pot Suzuki/Heck sequence for the synthesis of (E)-stilbenes featuring a recyclable silica-supported palladium catalyst via a multi-component reaction in 1,3-propanediol

The synthesis of (E)-stilbenes was performed following a one-pot Suzuki/Heck sequence through the use of potassium vinyltrifluoroborate. The combination of heterogeneous palladium/silica (Pd/SiO2) catalyst with potassium phosphate monohydrate (K3PO4?H 2O) as base resulted in useful to good isolated yields regardless of the ortho-, meta- or para-substitution of the aryl halides employed. In a sustainable approach, we found that bio-sourced 1,3- propanediol could advantageously replace N-methylpyrrolidone (NMP) as similar yields were obtained. Moreover, the reactivity gap between aryl iodides and bromides resulting from the use of 1,3-propanediol allowed an efficient multi-component approach toward the synthesis of (E)-stilbenes. Furthermore, this heterogeneous catalyst was found to be extremely robust despite the use of aerobic conditions and was successfully re-used over several cycles.