69891-44-7 Usage
Description
(R)-(-)-2-(P-TOLUENESULFONATE)-1,2-PROPANOL, with the chemical formula C10H14O3S, is a colorless to light yellow liquid featuring a chiral center and a faint, sweet odor. It is soluble in most organic solvents and exists in two enantiomeric forms, with the (R)-(-) enantiomer being the more commonly utilized. (R)-(-)-2-(P-TOLUENESULFONATE)-1,2-PROPANOL serves as a crucial chiral resolving agent in organic synthesis, particularly for the resolution of amines and alcohols.
Uses
Used in Pharmaceutical Industry:
(R)-(-)-2-(P-TOLUENESULFONATE)-1,2-PROPANOL is used as a chiral resolving agent for the separation and purification of enantiomers. This is essential in the production of pharmaceuticals and other fine chemicals, as the different enantiomers of a compound can exhibit distinct biological activities and effects.
Used in Agrochemical Industry:
In the agrochemical sector, (R)-(-)-2-(P-TOLUENESULFONATE)-1,2-PROPANOL is employed as a chiral resolving agent to ensure the correct enantiomer is used in the synthesis of agrochemicals. This is vital because the desired biological activity and safety profile of these compounds often depend on the specific enantiomer.
Overall, (R)-(-)-2-(P-TOLUENESULFONATE)-1,2-PROPANOL plays a significant role in various industries, particularly in the pharmaceutical and agrochemical sectors, due to its ability to separate and purify enantiomers, which is crucial for the development and production of effective and safe compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 69891-44-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,9,8,9 and 1 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 69891-44:
(7*6)+(6*9)+(5*8)+(4*9)+(3*1)+(2*4)+(1*4)=187
187 % 10 = 7
So 69891-44-7 is a valid CAS Registry Number.
InChI:InChI=1/C10H14O4S/c1-8-3-5-10(6-4-8)15(12,13)14-9(2)7-11/h3-6,9,11H,7H2,1-2H3/t9-/m1/s1
69891-44-7Relevant articles and documents
Highly Regioselective and Stereospecific Functionalization of 1,2-Proanediol with Trimethyl(X)silanes Employing the 1,3,2λ5-Dioxaphospholane Methodology
Mathieu-Pelta, Isabel,Evans, Slayton A.
, p. 3409 - 3413 (2007/10/02)
The regioselective ring opening of (S)-4-methyl-2,2,2-triphenyl-1,3,2λ5-dioxaphospholanes (2) was initiated with several trimethylsilyl reagents (Me3SiX: X = PhS, I, Br; Cl, CN, and N3) to afford the regioisomeric (silyloxy)phosphonium salts.A stereospecific extrusion of triphenylphosphine oxide from these oxyphosphonium salts gave predominatly the thermodynamically less stable C-2-X-substituted derivatives with nearly complete inversion of stereochemistry at the C-2 stereogenic center (i.e., X = PhS).
