698982-90-0

Basic information

• Product Name: (3-bromophenyl)-(2-fluorophenyl)methanone
• Synonyms: (3-bromophenyl)-(2-fluorophenyl)methanone
• CAS NO: 698982-90-0
• Molecular Weight: 279.108
• Mol File: 698982-90-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (3-bromophenyl)-(2-fluorophenyl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (3-bromophenyl)-(2-fluorophenyl)methanone(698982-90-0)
• EPA Substance Registry System: (3-bromophenyl)-(2-fluorophenyl)methanone(698982-90-0)

Safety Data

• Hazardous Substances Data: 698982-90-0(Hazardous Substances Data)

Upstream product

• 198967-24-7 2-fluoro-N-methoxy-N-methyl-benzamide 
• 108-36-1 1,3-dibromobenzene 
• 446-52-6 2-Fluorobenzaldehyde 
• 698982-09-1 (3-bromophenyl)(2-fluorophenyl)methanol 

Downstream Products

• 1220124-02-6 [(3-bromophenyl)-(2-fluorophenyl)ketone]thiosemicarbazone 
• 698983-01-6 bromo-3-((3-bromophenyl)(2-fluorophenyl)methyl)benzene 
• 608537-07-1 4-(3-{(2-fluorophenyl)[3-(3-methoxycarbonyl-3-oxopropionyl)phenyl]methyl}phenyl)-2,4-dioxobutyric acid methyl ester 
• 608536-98-7 1-{3-[(3-acetylphenyl)(2-fluorophenyl)methyl]phenyl}ethanone 
• 698982-96-6 bis(3-bromophenyl)(2-fluorophenyl)methanol 

Relevant articles and documents

Design, synthesis, and biological evaluation of potent thiosemicarbazone based cathepsin L inhibitors

A small library of 36 functionalized benzophenone thiosemicarbazone analogs has been prepared by chemical synthesis and evaluated for their ability to inhibit the cysteine proteases cathepsin L and cathepsin B. Inhibitors of cathepsins L and B have the potential to limit or arrest cancer metastasis. The six most active inhibitors of cathepsin L (IC50 50 > 10,000 nM). The most active analog in the series, 3-bromophenyl-2′-fluorophenyl thiosemicarbazone 1, also efficiently inhibits cell invasion of the DU-145 human prostate cancer cell line.