70006-59-6Relevant articles and documents
Linker-modified quinoline derivatives targeting HIV-1 integrase: Synthesis and biological activity
Benard, Christophe,Zouhiri, Fatima,Normand-Bayle, Marie,Danet, Michele,Desmaele, Didier,Leh, Herve,Mouscadet, Jean-Francois,Mbemba, Gladys,Thomas, Claire-Marie,Bonnenfant, Sabine,Le Bret, Marc,D'Angelo, Jean
, p. 2473 - 2476 (2007/10/03)
A novel series of HIV-1 integrase inhibitors was synthesized and tested in both in vitro and ex vivo assays. These inhibitors are featured by the presence of a quinoline subunit and an ancillary aromatic ring linked by functionalized spacers such as amide