70015-86-0 Usage
Description
1-(2-chloroethyl)-1-nitroso-3-(3-pyridylmethyl-1-oxy)urea, commonly known as chlormethine or mechlorethamine, is a highly reactive alkylating agent utilized in cancer chemotherapy. It is characterized by its ability to bind to and alkylate the guanine bases in DNA, causing cross-linking and disruption of the DNA structure, which ultimately leads to cell death. Chlormethine is recognized for its effectiveness in treating specific types of cancer and can be administered through various methods, including oral, intravenous, or topical application.
Uses
Used in Cancer Treatment:
Chlormethine is employed as a chemotherapeutic agent, particularly for the treatment of Hodgkin's lymphoma, non-Hodgkin's lymphoma, and certain types of leukemia. It modulates the DNA structure within cancer cells, disrupting their replication and growth, and is often used in combination with other chemotherapy drugs to enhance treatment efficacy.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, chlormethine is used as a key component in the development of cancer treatment drugs. Its alkylating properties make it a valuable asset in the creation of medications designed to combat various forms of cancer.
Despite its effectiveness in treating certain types of cancer, chlormethine can cause severe side effects and has a narrow therapeutic window, necessitating close monitoring during treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 70015-86-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,0,0,1 and 5 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 70015-86:
(7*7)+(6*0)+(5*0)+(4*1)+(3*5)+(2*8)+(1*6)=90
90 % 10 = 0
So 70015-86-0 is a valid CAS Registry Number.
InChI:InChI=1/C9H11ClN4O3/c10-3-5-14(12-16)9(15)11-6-8-2-1-4-13(17)7-8/h1-2,4,7H,3,5-6H2,(H,11,15)
