7008-63-1

Basic information

• Product Name: IMidazo[2,1-b]thiazole,6-phenyl-
• Synonyms: IMidazo[2,1-b]thiazole,6-phenyl-;6-phenyl-Imidazo[2,1-b]thiazole
• CAS NO: 7008-63-1
• Molecular Formula: C₁₁H₈N₂S
• Molecular Weight: 200.25962
• Mol File: 7008-63-1.mol
• Article Data: 33

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.29g/cm³
• Refractive Index: 1.712
• Storage Temp.: 2-8°C
• CAS DataBase Reference: IMidazo[2,1-b]thiazole,6-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: IMidazo[2,1-b]thiazole,6-phenyl-(7008-63-1)
• EPA Substance Registry System: IMidazo[2,1-b]thiazole,6-phenyl-(7008-63-1)

Safety Data

• Hazardous Substances Data: 7008-63-1(Hazardous Substances Data)

Usage

General Description

Imidazo[2,1-b]thiazole,6-phenyl- is a chemical compound with a molecular formula C11H8N2S. It is a heterocyclic compound containing both imidazole and thiazole rings, with a phenyl group attached at the 6-position. Imidazo[2,1-b]thiazole,6-phenyl- has been studied for its potential biological and pharmaceutical activities, with reported effects on various biological targets and pathways. Imidazo[2,1-b]thiazole,6-phenyl- has shown promise as a potential drug candidate for the treatment of various diseases, and its chemical structure makes it a valuable scaffold for the development of new therapeutic agents. It is used as a reagent in organic synthesis and medicinal chemistry research for the development of new pharmaceuticals.

InChI:InChI=1/C11H8N2S/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10/h1-8H

Upstream product

• 96-50-4 2-thiazolylamine 
• 70-11-1 α-bromoacetophenone 
• 101496-48-4 2-(4-phenyl-1⁽³⁾H-imidazol-2-ylmercapto)-acetaldehyde-diethylacetal 
• 127801-93-8 ethyl 6-phenylimidazo<2,1-b>thiazole-5-carboxylate 
• 6692-24-6 2-imino-3-phenacyl-2,3-dihydrothiazole 
• 7664-93-9 sulfuric acid 
• 7257-94-5 1-phenyl-2-(p-tolylsulfonyloxy)ethanone 
• 98-86-2 acetophenone 
• 55919-47-6 ethyl 2-bromo-3-oxo-3-phenylpropionate 
• 6857-34-7 4-phenyl-1,3-dihydro-2H-imidazole-2-thione 
• 389614-52-2 α-[(2,4-dinitrobenzene)sulfonyl]oxyacetophenone 
• 6039-97-0 3H-thiazol-2-one 
• 100-41-4 ethylbenzene 
• 349481-08-9 ethyl 6-phenylimidazo[2,1-b][1,3]thiazole-2-carboxylate 

Downstream Products

• 99974-06-8 4-imidazo[2,1-b]thiazol-6-yl-benzenesulfonic acid 
• 16311-32-3 (6-phenyl-imidazo[2,1-b]thiazol-5-yl)-succinic acid 
• 14954-71-3 6-phenyl-5-phenylazo-imidazo[2,1-b]thiazole 
• 14954-66-6 5-(4-nitro-phenylazo)-6-phenyl-imidazo[2,1-b]thiazole 
• 14956-60-6 5-(2-nitro-phenylazo)-6-phenyl-imidazo[2,1-b]thiazole 
• 74630-73-2 6-phenylimidazo[2,1-b]thiazole-5-carbaldehyde 
• 14956-61-7 5-(3-nitro-phenylazo)-6-phenyl-imidazo[2,1-b]thiazole 
• 16311-29-8 N,N''-(6-phenyl-imidazo[2,1-b]thiazole-2,5-diyl)-bis-hydrazine-N,N'-dicarboxylic acid tetraethyl ester 
• 93327-30-1 4-(6-phenyl-imidazo[2,1-b]thiazol-5-ylazo)-benzenesulfonic acid 
• 99866-35-0 5-bromo-6-phenylimidazo[2,1-b]thiazole 
• 99866-92-9 2-nitroso-6-phenyl-imidazo[2,1-b]thiazole 
• 16311-38-9 5-nitro-6-(4-nitro-phenyl)-imidazo[2,1-b]thiazole 
• 7120-14-1 6-p-nitrophenylimidazo<2,1-b>thiazole 
• 16311-34-5 5-nitroso-6-phenylimidazo[2,1-b][1,3]thiazole 

Relevant articles and documents

Synthesis, crystal structure, antimicrobial activity and docking studies of new imidazothiazole derivatives

A series of imidazothiazole derivatives were synthesized via Claisen–Schmidt condensation of aldehyde 3, and different methyl ketones and their chemical structures were confirmed using 13C NMR, 1H NMR and LC–MS. In addition, the mole

Electrochemical Oxidative C3 Acyloxylation of Imidazo[1,2- a]pyridines with Hydrogen Evolution

The C3-functionalized imidazo[1,2-a]pyridines are versatile nitrogen-fused heterocycles; however, the methods for the C3 acyloxylation of imidazo[1,2-a]pyridines have never been reported. Herein we demonstrate the electrochemical oxidative C3 acyloxylation of imidazo[1,2-a]pyridines for the first time. Notably, by using electricity, the electrochemical oxidative C3 acyloxylation of imidazo[1,2-a]pyridines was carried out under mild conditions. Moreover, in addition to aromatic carboxylic acids, alkyl carboxylic acids were also competent substrates.

CuCl2-catalyzed N[sbnd]O bond cleavage of oxime esters: Approach to imidazoheterocycles and furo[3,2-c]chromenyl fused imidazoles

An articulate approach to a diverse set of imidazoheterocycles in good to high yields via a copper-catalyzed aza-annulation of several oxime esters with a group of 2-amino-azaarenes was developed. The above cyclization reaction probably proceeds via a single electron transfer process which embodies a new technique for creating two new C[sbnd]N bonds for imidazole ring synthesis. Gratifyingly, the implementation of this chemistry could be further stretched to the synthesis of a novel class of fused imidazoles bearing a furo[3,2-c]chromene moiety via a sequential C[sbnd]N bond formation, followed by C(sp2)-H functionalization/5-endo-dig-oxacyclization (C[sbnd]C and C[sbnd]O bonds) of in situ produced fused imidazoles with cyclic enynones in the presence of copper(II) as a π-electrophilic Lewis acid catalyst.