70094-79-0

Basic information

• Product Name: genipin
• CAS NO: 70094-79-0
• Molecular Weight: 226.229
• Mol File: 70094-79-0.mol
• Article Data: 15

Chemical Properties

• CAS DataBase Reference: genipin(CAS DataBase Reference)
• NIST Chemistry Reference: genipin(70094-79-0)
• EPA Substance Registry System: genipin(70094-79-0)

Safety Data

• Hazardous Substances Data: 70094-79-0(Hazardous Substances Data)

Upstream product

• 24512-63-8 geniposide 
• 1174680-01-3 genipin 1-O-β-D-isomaltoside 
• 67-48-1 choline chloride 
• 24512-63-8 geniposide 

Downstream Products

• 24512-63-8 geniposide 
• 69977-52-2 1-methoxygenipin 
• 206755-40-0 1-benzyloxygenipin 

Relevant articles and documents

Transformation of geniposide into genipin by immobilized β-glucosidase in a two-phase aqueous-organic system

Genipin is the bioactive compound of geniposide and a natural cross-linking agent. In order to improve the preparation process of genipin, the hydrolysis of geniposide to genipin by immobilized β-glucosidase in an aqueous-organic two-phase system was studied. β-Glucosidase was immobilized by the crosslinking-embedding method using sodium alginate as the carrier. The optimum reaction temperature, pH value and time were 55 °C, 4.5 and 2.5 h, respectively. To reduce genipin hydrolysis and byproduct production the reaction was carried out in an aqueous-organic two-phase system comprising ethyl acetate and sodium acetate buffer. The product was analyzed by HPLC, UV, IR, and NMR. The yield of genipin was 47.81% and its purity was over 98% (HPLC).

A PROCESS FOR PRODUCING GARDENIA BLUE PIGMENT FORM GENIPOSIDE

A process for producing the gardenia blue pigment comprising treating geniposide with a glycosidase to obtain a hydrolysate, extracting the hydrolysate with a solvent and removing the solvent after the extraction to obtain a product comprising genipin, reacting the product comprising genipin with an amino acid and/or a salt thereof under an atmosphere of inert gas, and introducing oxygen after genipin is consumed to produce the gardenia blue pigment. The process is easy-to-workup and suitable for industry and the obtained gardenia blue pigment is bright and suitable for industrial application.

BICYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF FOR TREATING STROKE AND USE THEREOF

The present disclosure relates to a bicyclic compound, a pharmaceutical composition thereof, and its novel use. More particularly, the present disclosure relates to the bicyclic compound according to Formula I or Formula II, the pharmaceutical composition for treating a stroke, and the use of the bicyclic compound treating the stroke.