7062-40-0

Basic information

• Product Name: 5-BROMO-2-METHOXYPHENYLACETONITRILE
• Synonyms: 5-BROMO-2-METHOXYPHENYLACETONITRILE;2-(5-broMo-2-Methoxyphenyl)acetonitrile;Benzeneacetonitrile, 5-broMo-2-Methoxy-;5-BroMo-2-Methoxybenzyl cyanide;5-Bromo-2-methoxybenzyl cyanide, 4-Bromo-2-(cyanomethyl)anisole
• CAS NO: 7062-40-0
• Molecular Formula: C₉H₈BrNO
• Molecular Weight: 226.07
• Product Categories: Aromatic Nitriles
• Mol File: 7062-40-0.mol
• Article Data: 4

Chemical Properties

• Melting Point: 61-63°C
• Boiling Point: 580.8°C at 760 mmHg
• Flash Point: 305.1°C
• Appearance: /
• Density: 1.37g/cm³
• Vapor Pressure: 1.75E-13mmHg at 25°C
• Refractive Index: 1.698
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 5-BROMO-2-METHOXYPHENYLACETONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMO-2-METHOXYPHENYLACETONITRILE(7062-40-0)
• EPA Substance Registry System: 5-BROMO-2-METHOXYPHENYLACETONITRILE(7062-40-0)

Safety Data

• Hazard Codes: Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39
• RIDADR: 3439
• HazardClass: IRRITANT, IRRITANT-HARMFUL
• Hazardous Substances Data: 7062-40-0(Hazardous Substances Data)

Usage

Description

5-BROMO-2-METHOXYPHENYLACETONITRILE, also known as 2-(5-Bromo-2-methoxyphenyl)acetonitrile, is an organic compound that serves as a crucial intermediate in the synthesis of various chemical compounds and pharmaceuticals. It is characterized by its unique molecular structure, which includes a bromo and methoxy group attached to a phenyl ring, with an acetonitrile group as a side chain. This structure endows it with specific chemical properties that make it valuable in the field of organic synthesis.

Uses

Used in Pharmaceutical Industry:
5-BROMO-2-METHOXYPHENYLACETONITRILE is used as a synthetic intermediate for the production of various pharmaceutical compounds. Its unique molecular structure allows for the creation of a wide range of derivatives with potential therapeutic applications, making it a valuable asset in the development of new drugs.
Used in Chemical Synthesis:
In the field of organic chemistry, 5-BROMO-2-METHOXYPHENYLACETONITRILE is used as a key building block for the synthesis of various organic compounds. Its versatile structure enables chemists to perform a range of reactions, such as substitution, addition, and condensation, to create new molecules with diverse properties and applications.
Used in Research and Development:
5-BROMO-2-METHOXYPHENYLACETONITRILE is also utilized in research and development laboratories for the exploration of new chemical reactions and the development of innovative synthetic methods. Its unique structure and reactivity make it an ideal candidate for studying various aspects of organic chemistry, including reaction mechanisms, stereochemistry, and catalyst design.

InChI:InChI=1/C21H22N4O2S/c1-4-8-28-20-24-18-17(19(27)25-20)15(12-6-5-7-22-11-12)16-13(23-18)9-21(2,3)10-14(16)26/h4-7,11,15H,1,8-10H2,2-3H3,(H2,23,24,25,27)

Upstream product

• 7017-52-9 4-bromo-2-(chloromethyl)-1-methoxybenzene 
• 151-50-8 potassium cyanide 
• 80866-82-6 5-bromo-2-methoxy-benzyl alcohol 
• 25016-01-7 5-bromo-2-methoxybenzaldehyde 
• 2316-64-5 5-bromo-2-hydroxybenzyl alcohol 
• 7035-03-2 2-methoxy-benzeneacetonitrile 

Downstream Products

• 294860-58-5 methyl 2-(5-bromo-2-methoxyphenyl)acetate 
• 863562-62-3 5-bromo-2-methoxyphenylacetic acid ethyl ester 
• 7017-48-3 2-(5-bromo-2-methoxyphenyl)acetic acid 
• 73775-39-0 2-(5-Bromo-2-methoxy-phenyl)-acetimidic acid ethyl ester; hydrochloride 
• 149488-99-3 2-(2-methoxy-5-bromophenyl)-1-aminoethane 
• 163813-58-9 N-<2-(2-methoxy-5-bromophenyl)ethyl>acetamide 
• 73775-42-5 2-(5-Bromo-2-methoxy-phenyl)-acetamidine; hydrochloride 
• 73775-47-0 2-(2-Methoxy-5-bromobenzyl)-2-imidazoline hydrochloride 

Relevant articles and documents

Rapid and Simple Access to α-(Hetero)arylacetonitriles from Gem-Difluoroalkenes

A scalable cyanation of gem-difluoroalkenes to (hetero)arylacetonitrile derivatives was developed. This strategy features mild reaction conditions, excellent yields, wide substrate scope, and broad functional group tolerance. Significantly, in this reacti

TRIAZOLONE COMPOUNDS AND USES THEREOF

The invention disclosed herein is directed to compounds of Formula (I) and pharmaceutically acceptable salts thereof, which are useful in the treatment of prostate, breast, colon, pancreatic, human chronic lymphocytic leukemia, melanoma and other cancers. The invention also comprises pharmaceutical compositions comprising a therapeutically effective amount of compound of Formula (I), or a pharmaceutically acceptable salt thereof. The invention disclosed herein is also directed to methods of treating prostate, breast, ovarian, liver, kidney, colon, pancreatic, human chronic lymphocytic leukemia, melanoma and other cancers. The invention disclosed herein is further directed to methods of treating prostate, breast, colon, pancreatic, chronic lymphocytic leukemia, melanoma and other cancers comprising administration of a of a therapeutically effective amount of a selective PPARα antagonist. The compounds and pharmaceutical compositions of the invention are also useful in the treatment of viral infections, such as HCV infections and HIV infections. The invention disclosed herein is also directed to a methods of preventing the onset of and/or recurrence of acute and chronic myeloid leukemia, as well as other cancers, comprising administration of a of a therapeutically effective amount of a selective PPARα antagonist.