7064-31-5

Basic information

• Product Name: 5-(4-BROMOPHENYL)ISOXAZOLE
• Synonyms: BUTTPARK 32\03-50;5-(4-BROMOPHENYL)ISOXAZOLE
• CAS NO: 7064-31-5
• Molecular Formula: C₉H₆BrNO
• Molecular Weight: 224.05
• Mol File: 7064-31-5.mol
• Article Data: 14

Chemical Properties

• Melting Point: 114 °C
• Boiling Point: 333°Cat760mmHg
• Flash Point: 155.2°C
• Appearance: /
• Density: 1.524g/cm³
• Vapor Pressure: 2.09E-14mmHg at 25°C
• Refractive Index: 1.708
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: -3.18±0.10(Predicted)
• CAS DataBase Reference: 5-(4-BROMOPHENYL)ISOXAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-BROMOPHENYL)ISOXAZOLE(7064-31-5)
• EPA Substance Registry System: 5-(4-BROMOPHENYL)ISOXAZOLE(7064-31-5)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-41-37/38-22
• Safety Statements: 26-36/37/39-39
• Hazardous Substances Data: 7064-31-5(Hazardous Substances Data)

Usage

Uses

5-(4-Bromophenyl)isoxazole is used as an active pharmaceutical ingredients.

InChI:InChI=1/C31H34N6O3S2/c1-6-14-35-27(34-15-10-11-19(2)18-34)23(20(3)24(17-32)28(35)38)16-25-29(39)36(31(41)42-25)26-21(4)33(5)37(30(26)40)22-12-8-7-9-13-22/h7-9,12-13,16,19H,6,10-11,14-15,18H2,1-5H3

Upstream product

• 73387-60-7 1-(4-bromophenyl)-3-(dimethylamino)prop-2-en-1-one 
• 14153-75-4 p-bromobenzoylacetaldehyde 
• 99-90-1 para-bromoacetophenone 
• 91869-64-6 1-[(E)-1-(4-Bromo-phenyl)-3-dimethylamino-prop-2-en-(E)-ylideneamino]-4,6-diphenyl-1H-pyridin-2-one 
• 91869-67-9 N-(α-methyl-4-bromobenzylidenamino)-4,6-diphenyl-2-pyridone 
• 73387-60-7 (2E)-1-(4-bromophenyl)-3-(dimethylamino)prop-2-en-1-one 
• 1606168-00-6 C₁₄H₁₁BrNO⁽¹⁺⁾*Br^(1-) 
• 54012-24-7 1-(4-bromophenyl)-2-propyn-1-one 
• 37614-58-7 3-(4-bromophenyl)prop-2-yn-1-ol 

Downstream Products

• 176961-35-6 N-(3,4-Dimethyl-5-isoxazolyl)-N-[(2-methoxyethoxy)methyl]-4'-(5-isoxazolyl)[1,1'-biphenyl]-2-sulfonamide 
• 666721-45-5 4-[4-(Isoxazol-5-yl)phenyl]-N-(2-morpholin-4-ylethyl)thiophene-2-carboxamide 
• 1386231-62-4 potassium (4-(isoxazol-5-yl)phenyl)trifluoroborate 

Relevant articles and documents

Preparation method of isoxazole derivative

The invention relates to a preparation method of an isoxazole derivative, which comprises the following steps of mixing an propargyl alcohol derivative, a halogen source, an acid and a solvent, and heating to react; adding the hydroxylamine into the react

A novel synthesis of 5-substituted isoxazoles from propargylic amines and N-hydroxyphthalimide

A mild and efficient method for the synthesis of 5-substituted isoxazoles through cyclization of propargylic amines with N-hydroxyphthalimide (NHPI) under metal-free conditions was developed.

Reactions of trans-1-(β-aroylvinyl)pyridinium bromides with hydroxylamine hydrochloride

Reactions of trans-1-(β-aroylvinyl)pyridinium bromides with hydroxylamine hydrochloride lead to a mixture of substituted isoxazoles regardless of the substituent nature in the aromatic core and the solvent.