70726-17-9

Basic information

• Product Name: Phosphonium, [(2-hydroxy-5-nitrophenyl)methyl]triphenyl-, chloride
• CAS NO: 70726-17-9
• Molecular Formula: C25H21NO3P.Cl
• Molecular Weight: 449.873
• Mol File: 70726-17-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Phosphonium, [(2-hydroxy-5-nitrophenyl)methyl]triphenyl-, chloride(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonium, [(2-hydroxy-5-nitrophenyl)methyl]triphenyl-, chloride(70726-17-9)
• EPA Substance Registry System: Phosphonium, [(2-hydroxy-5-nitrophenyl)methyl]triphenyl-, chloride(70726-17-9)

Safety Data

• Hazardous Substances Data: 70726-17-9(Hazardous Substances Data)

Upstream product

• 100-02-7 4-nitro-phenol 
• 2973-19-5 2-hydroxy-5-nitrobenzyl chloride 
• 603-35-0 triphenylphosphine 

Downstream Products

• 141627-42-1 (2-butyl-5-nitrobenzofuran-3-yl)(4-methoxyphenyl)methanone 
• 141645-16-1 2-n-butyl-3-(4-hydroxybenzoyl)-5-nitrobenzofuran 
• 133238-87-6 2-(n-butyl)-5-nitrobenzofuran 
• 23136-39-2 2-acetyl-5-nitrobenzofuran 
• 101315-49-5 (5-nitrobenzofuran-2-yl)(phenyl)methanone 

Relevant articles and documents

Preparation method of key intermediate of dronedarone

The invention relates to a preparation method of a key intermediate of drug dronedarone for treating atrial fibrillation, and specifically relates to the 2-butyl-3-(4-hydroxybenzoyl)-5-nitrobenzofuran. According to the method provided by the invention, a series of reactions are performed by using inexpensive p-nitrophenol as a starting material to prepare the 2-butyl-3-(4-hydroxybenzoyl)-5-nitrobenzofuran, the process is smooth, the costs are lower, the yield is higher, the controllability is stronger, and the method is suitable for industrial production.