70882-08-5Relevant articles and documents
A Rare Alder-ene Cycloisomerization of 1,6-Allenynes
Joyce, Liam M.,Drew, Melanie A.,Tague, Andrew J.,Thaima, Thanaphat,Gouranourimi, Ali,Ariafard, Alireza,Pyne, Stephen G.,Hyland, Christopher J. T.
, (2022/02/07)
Thermally induced cycloisomerization reactions of 1,6-allenynes gives α-methylene-γ-lactams via intramolecular Alder-ene reactions. The mechanism is supported by computational and deuterium labelling studies. This thermal, non-radical method enables the d
Copper(II)-Promoted Cyclization/Difunctionalization of Allenols and Allenylsulfonamides: Synthesis of Heterocycle-Functionalized Vinyl Carboxylate Esters
Casavant, Barbara J.,Khoder, Zainab M.,Berhane, Ilyas A.,Chemler, Sherry R.
supporting information, p. 5958 - 5961 (2016/01/09)
A unique method to affect intramolecular aminooxygenation and dioxygenation of allenols and allenylsulfonamides is described. These operationally simple reactions occur under neutral or basic conditions where copper(II) carboxylates serve as reaction promoter, oxidant, and carboxylate source. Moderate to high yields of heterocycle-functionalized vinyl carboxylate esters are formed with moderate to high levels of diastereoselectivity. Such vinyl carboxylate esters could serve as precursors to α-amino and α-oxy ketones and derivatives thereof.
Pd-catalyzed asymmetric synthesis of N-allenyl amides and their Au-catalyzed cycloisomerizative hydroalkylation: A new route toward enantioenriched pyrrolidones
Boutier, Audrey,Kammerer-Pentier, Claire,Krause, Norbert,Prestat, Guillaume,Poli, Giovanni
supporting information; experimental part, p. 3840 - 3844 (2012/06/15)
Palladium to make them, gold to cyclize them! Gold-catalyzed cycloisomerizative hydroalkylation of N-allenyl amides affords regioselectively 4-vinyl-γ-lactams. This transformation is stereospecific and takes place with a total axis-to-center chirality tra