70946-18-8

Basic information

• Product Name: Benzamide, N,N-diethyl-3,4-dimethoxy-
• CAS NO: 70946-18-8
• Molecular Formula: C13H19NO3
• Molecular Weight: 237.299
• Mol File: 70946-18-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Benzamide, N,N-diethyl-3,4-dimethoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N,N-diethyl-3,4-dimethoxy-(70946-18-8)
• EPA Substance Registry System: Benzamide, N,N-diethyl-3,4-dimethoxy-(70946-18-8)

Safety Data

• Hazardous Substances Data: 70946-18-8(Hazardous Substances Data)

Upstream product

• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 109-89-7 diethylamine 
• 3535-37-3 3,4-dimethoxybenzoic acid chloride 
• 98-01-1 furfural 
• 5460-32-2 1-iodo-3,4-dimethoxybenzene 
• 121-44-8 triethylamine 
• 617-84-5 N-formyldiethylamine 
• 93-07-2 Veratric acid 
• 685876-77-1 3,4-diacetoxy-benzoic acid diethylamide 
• 57929-25-6 3,4-(diacetyloxy)benzoyl chloride 
• 37673-01-1 2-(N,N-diethylamino)-2-(3,4-dimethoxyphenyl)acetonitrile 
• 137609-03-1 3,4-dihydroxy-benzoic acid diethylamide 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 1228657-94-0 C₁₃H₁₈ClNO₃ 
• 5417-17-4 2-chloro-3,4-dimethoxybenzaldehyde 
• 116642-29-6 2-(5-Acetyl-furan-2-ylmethyl)-3,4-dimethoxy-benzoic acid 
• 85370-73-6 N,N-diethyl-2-bromo-3,4-dimethoxy-6-methylbenzamide 
• 90359-82-3 4,5-dimethoxy-7-methyl-3-(3',5'-dimethoxyphenyl)phthalide 
• 113975-92-1 N,N-diethyl-4,5-dimethoxy-2-methyl-benzamide 
• 121424-98-4 N,N-diethyl-3,4-dimethoxy-6-formyl-2-(trimethylsilyl)benzamide 
• 121424-97-3 N,N-diethyl-6-deuterio-3,4-dimethoxy-2-(trimethylsilyl)benzamide 
• 121425-07-8 N,N-diethyl-2-deuterio-4,5-dimethoxybenzamide 
• 73540-64-4 4,5-dimethoxy-3-phenylisobenzofuran-1(3H)-one 
• 518-90-1 3,4-dimethoxy-phthalic acid 
• 90359-81-2 N,N-diethyl-3,4-dimethoxy-6-methyl-2-(trimethylsilyl)benzamide 
• 213686-31-8 2(2'furfuryl)-3,4-dimethoxy-benzoic acid 
• 70946-10-0 N,N-diethyl 3,4-dimethoxy-2-methylbenzamide 

Relevant articles and documents

HMF and furfural: Promising platform molecules in rhodium-catalyzed carbonylation reactions for the synthesis of furfuryl esters and tertiary amides

A biomass involved rhodium-catalyzed carbonylative synthesis of furfuryl esters and tertiary amides has been developed. 5-Hydroxymethylfurfural (HMF) was used as both substrate and CO surrogate for the first time in a carbonylation reaction, and both alkyl and aryl iodides were tolerated well to afford the desired furfuryl esters in moderate to good yields. In addition, furfural was also utilized as a CO source for the synthesis of tertiary amides. A variety of tertiary amides were obtained in moderate to excellent yields with good functional groups compatibility. Notably, tertiary amines were used as the amine source through a C[sbnd]N bond cleavage pathway in the absence of additional oxidant.

Radical mediated-direct conversion of aldehydes into acid bromides

A method of preparing acid bromides directly from aldehydes with Br3CCO2Et under radical conditions was developed. Aromatic aldehydes with electron-donating group were found to be more reactive than aromatic aldehydes with electron-w

Synthesis of pentasubstituted benzamides via orthometallation: Base and substituent effects

The synthesis of diversely substituted ori/io-methyl JV,./V-diethylbenzamides using the orthometallation concept is described. A dramatic effect of the substituents and the additive TMEDA is observed during metallation ortho to the N1N-diethylcarboxamido group. Molecular modeling confirms the conformational effect of substituents. A role for the TMEDA additive is proposed. Elscvier,.