71030-35-8

Basic information

• Product Name: (+/-)12-HPETE
• Synonyms: 12-HYDROPEROXY-5Z,8Z,10E,14Z-EICOSATETRAENOIC ACID;(+/-)12-HPETE;12-Hydroperoxy-5,8,10,14-icosatetraenoic acid
• CAS NO: 71030-35-8
• Molecular Formula: C20H32O4
• Molecular Weight: 336.47
• Mol File: 71030-35-8.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (+/-)12-HPETE(CAS DataBase Reference)
• NIST Chemistry Reference: (+/-)12-HPETE(71030-35-8)
• EPA Substance Registry System: (+/-)12-HPETE(71030-35-8)

Safety Data

• Hazardous Substances Data: 71030-35-8(Hazardous Substances Data)

Usage

Uses

(+/-)12-HpETE is one of the six monohydroperoxy fatty acids.

Upstream product

• 506-32-1 all cis 5,8,11,14-eicosatetraenoic acid 
• 96349-33-6 (5Z,8Z)-9-[2-Bromo-3-((Z)-oct-2-enyl)-cyclopropyl]-nona-5,8-dienoic acid 

Relevant articles and documents

Physcomitrella patens has lipoxygenases for both eicosanoid and octadecanoid pathways

Mosses have substantial amounts of long chain C20 polyunsaturated fatty acids, such as arachidonic and eicosapentaenoic acid, in addition to the shorter chain C18 α-linolenic and linoleic acids, which are typical substrates of lipoxygenases in flowering p

Unified Mechanism for Polyunsaturated Fatty Acid Autooxidation. Competition of Peroxy Radical Hydrogen Atom Abstraction, β-Scission, and Cyclization

The autooxidation of linoleic (18:2) and arachidonic (20:4) acids with several cosubstrates was investigated.Cumene, tetralin, 1,4-cyclohexadiene, and 9,10-dihydroanthracene in benzene were used as cosubstrates for the oxidation of linoleic acid.The distribution of products, trans,cis diene hydroperoxides and trans,trans diene hydroperoxides, was dependent on the ability of cosubstrates to donate hydrogen atoms to linoleate peroxy radicals.Arachidonic acid was oxidized in mixtures of benzene/1,4-cyclohexadiene with linoleic acid internal standard.Product distribution of six hydroperoxyeicosatetraenoic acids (HPETE) derived from arachidonic acid was established at different concentrations of 1,4-cyclohexadiene in the solvent mixture.A kinetic expression is derived that is useful in describing polyunsaturated fatty acid oxidation product mixtures.By the use of this kinetic derivation, the rate of cyclization of peroxy free radicals derived from arachidonic acid was determined.