71035-26-2Relevant articles and documents
Silver-catalyzed efficient synthesis of enaminones from propargyl alcohols and amines
Li, Mengshun,Fang, Dongmei,Geng, Feng,Dai, Xianping
supporting information, p. 4747 - 4749 (2017/11/28)
Enaminones are used as the key intermediates to construct heterocyclic compounds with various bioactivities. In this study, a simple and efficient approach for the synthesis of enaminones via amination of propargyl alcohols was developed. Under the catalysis of Ag2CO3, the reaction proceeded smoothly to afford the desired products in good yields. Preliminary mechanism experiments showed that Ag2CO3 played an essential role in the procedure of the reaction.
Transformation of α-substituted propanols into γ-amino alcohols through nickel-catalyzed amination on the terminal γ-carbon of propanols
Ueno, Satoshi,Usui, Kazumi,Kuwano, Ryoichi
supporting information; experimental part, p. 1303 - 1307 (2011/07/08)
A nickel-phosphine complex was found to be effective as the catalyst for the transformation of alcohols into β-enaminones, which was successively converted into γ-amino alcohols by a conventional reductant. The sequential transformation is equivalent to the carbon-nitrogen bond formation at the γ-position of saturated alcohols. Georg Thieme Verlag Stuttgart · New York.
The influence of substituents on the photochemical generation and stability of 2-morpholinocyclopropanols
Weigel,Schiller,Reck,Henning
, p. 6737 - 6740 (2007/10/02)
By irradiation in oxygen-free ether α- or β-substituted β-morpholinopropiophenones 1a-c form the corresponding cyclopropanols 2 with 1-aryl and 2-morpholino group in a relative cis-configuration in high yields. The photocyclization of pure 1a-c enantiomer
