71066-01-8 Usage
General Description
(S)-2-tert-butoxycarbonylamino-heptanoic acid is a chemical compound with the molecular formula C13H25NO4. Commonly known as Boc-L-lysine, it is a derivative of the amino acid lysine and is often used in the synthesis of peptides and pharmaceuticals. The "Boc" in its name refers to the tert-butoxy-carbonyl protecting group, which is used to temporarily protect the amine group in organic synthesis. (S)-2-TERT-BUTOXYCARBONYLAMINO-HEPTANOIC ACID has applications in the field of medicinal chemistry and drug development, where it is used as a building block for creating peptide-based drugs and functional materials. Additionally, it may also be used in biochemical research and as a tool for studying protein structure and function.
Check Digit Verification of cas no
The CAS Registry Mumber 71066-01-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,0,6 and 6 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 71066-01:
(7*7)+(6*1)+(5*0)+(4*6)+(3*6)+(2*0)+(1*1)=98
98 % 10 = 8
So 71066-01-8 is a valid CAS Registry Number.
InChI:InChI=1/C12H23NO4/c1-5-6-7-8-9(10(14)15)13-11(16)17-12(2,3)4/h9H,5-8H2,1-4H3,(H,13,16)(H,14,15)/t9-/m0/s1
71066-01-8Relevant articles and documents
Inhibitors selective for HDAC6 in enzymes and cells
Gupta, Praveer K.,Reid, Robert C.,Liu, Ligong,Lucke, Andrew J.,Broomfield, Steve A.,Andrews, Melanie R.,Sweet, Matthew J.,Fairlie, David P.
supporting information; experimental part, p. 7067 - 7070 (2011/01/03)
Histone deacetylase inhibitors with anticancer or anti-inflammatory activity bind to Class I or Class I and II HDAC enzymes. Here we compare selectivity of inhibitors of a Class II HDAC enzyme (HDAC6) and find one that retains high selectivity in macrophages.
Use of (S)-N-tert-butoxycarbonylaziridine-2-carboxylate derivatives for α-amino acid synthesis
Baldwin, Jack E.,Farthing, Christopher N.,Russell, Andrew T.,Schofield, Christopher J.,Spivey, Alan C.
, p. 3761 - 3764 (2007/10/03)
(S)-tert-Butyl-N-tert-butoxycarbonylaziridine-2-carboxylate and (S)-tert-butyl-N-tert-butoxycarbonylaziridine-2-carboxamide were synthesised and found to react with copper 'catalysed' Grignard reagents to give protected α-amino acids in moderate to good yields.
