71082-53-6 Usage
Description
8-FLUOROQUINOLINE-3-CARBOXYLIC ACID is an organic compound characterized by the presence of a fluorine atom at the 8th position of the quinoline ring and a carboxylic acid functional group. It is known for its potential applications in various fields, particularly in the pharmaceutical and chemical industries, due to its unique structural properties and reactivity.
Uses
Used in Pharmaceutical Industry:
8-FLUOROQUINOLINE-3-CARBOXYLIC ACID is used as a reactant for the synthesis of an inhibitor of proteasome subunit Rpn11. This application is significant because proteasomes play a crucial role in cellular processes, and their inhibition can lead to the development of novel therapeutic strategies for various diseases, including cancer.
In the synthesis process, 8-FLUOROQUINOLINE-3-CARBOXYLIC ACID serves as a key building block, providing the necessary structural framework for the formation of the final inhibitor molecule. The fluorine atom at the 8th position enhances the reactivity and stability of the compound, making it an ideal candidate for further functionalization and optimization.
The development of inhibitors targeting proteasome subunit Rpn11 can have significant implications in the treatment of various diseases, as it may help in modulating the activity of specific cellular pathways and protein degradation processes. By using 8-FLUOROQUINOLINE-3-CARBOXYLIC ACID as a starting material, researchers can explore the potential of this compound in designing and developing novel therapeutic agents with improved efficacy and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 71082-53-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,1,0,8 and 2 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 71082-53:
(7*7)+(6*1)+(5*0)+(4*8)+(3*2)+(2*5)+(1*3)=106
106 % 10 = 6
So 71082-53-6 is a valid CAS Registry Number.
71082-53-6Relevant articles and documents
TRIAZOLE COMPOUNDS AS LIPOXYGENASE INHIBITORS
-
Page/Page column 46, (2008/06/13)
There is provided compounds of formula (I) wherein W is an optionally substituted aryl or heteroaryl group, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of the activity of a lipoxygenase (e.g. 15- lipoxygenase) is desired and/or required, and particularly in the treatment of inflammation.
