7113-05-5

Basic information

• Product Name: 2-phenylthiazole-4-carbonitrile
• Synonyms: 2-phenylthiazole-4-carbonitrile
• CAS NO: 7113-05-5
• Molecular Weight: 186.237
• Mol File: 7113-05-5.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 2-phenylthiazole-4-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenylthiazole-4-carbonitrile(7113-05-5)
• EPA Substance Registry System: 2-phenylthiazole-4-carbonitrile(7113-05-5)

Safety Data

• Hazardous Substances Data: 7113-05-5(Hazardous Substances Data)

Upstream product

• 857550-21-1 2-phenyl-1,3-thiazole-4-carboxamide 
• 7113-10-2 2-phenyl-1,3-thiazole-4-carboxylic acid 
• 2227-79-4 benzenecarbothioamide 
• 20949-81-9 2-phenyl-thiazole-4-carbaldehyde 
• 108735-87-1 2-phenyl-4-formyl-thiazole oxime 
• 59937-01-8 2-phenylthiazole-4-carboxylic acid ethyl ester 

Downstream Products

• 21917-78-2 4-ethoxy-1-(2-phenyl-thiazol-4-yl)-butan-1-one 
• 94487-81-7 N-hydroxy-2-phenyl-thiazole-4-carboximidic acid amide 
• 7113-14-6 2-phenylthiazole-4-carbothioamide 
• 1416716-40-9 2-phenyl-4-(1H-tetrazol-5-yl)thiazole 
• 65823-57-6 4-(4-chloro-phenyl)-2'-phenyl-[2,4']bithiazolyl 
• 1569318-98-4 C₁₉H₁₃N₃O₂S₂ 
• 7113-02-2 2-phenyl-1,3-thiazole-4-carboxylic acid methyl ester 
• 21917-82-8 8-acetoxy-3-phenyl-5,6-dihydro-thiazolo[3,4-a]pyridinylium; bromide 
• 21917-81-7 3-phenyl-8-oxo-5,6,7,8-tetrahydro-thiazolo[3,4-a]pyridinylium; bromide 
• 7113-10-2 2-phenyl-1,3-thiazole-4-carboxylic acid 
• 10477-28-8 4,2'-diphenyl-[2,4']bithiazolyl 

Relevant articles and documents

Efficient nitriding reagent and application thereof

The invention discloses an efficient nitriding reagent and application thereof, wherein the nitriding reagent comprises nitrogen oxide, an active agent, a reducing agent and an organic solvent. By applying the nitriding reagent, nitrogen-containing compounds such as amide, nitrile and the like can be produced, and the method is simple in condition, low in waste discharge amount and simple in reaction equipment.

Synthesis, Characterization, and Antimicrobial Screening of 4″-methyl-2,2″-diaryl-4,2′:4′,5″-terthiazole Derivatives

A series of novel 4″-methyl-2,2″-diaryl-4,2′:4′,5″-terthiazole (8a-p) derivatives has been synthesized and screened for antibacterial activity against four pathogenic bacteria, Escherichia coli, Pseudomonas flurescence, Staphylococcus aureus, and Bacillus subtilis. Among them, compounds 8a and 8j exhibited excellent antibacterial activity with minimum inhibitory concentration range of 1.0 to 5.3?μg/mL and compounds 8m and 8p exhibited moderate to good antibacterial activity with minimum inhibitory concentration range of 16.9 to 29.7?μg/mL against all tested strains. All the synthesized compounds were screened for their in vitro antifungal activity against Cocinida candida. Most of the compounds reported moderate antifungal activity. This study provides valuable directions to our ongoing endeavor of rationally designing more potent antimicrobial agent.

The effect of some 4,2 and 5,2 bisthiazole derivatives on nitro-oxidative stress and phagocytosis in acute experimental inflammation

Nineteen bisthiazoles were tested in order to assess their anti-inflammatory and antioxidant properties. First, we evaluated the in vitro direct antioxidant capacity of the bisthiazoles using the DPPH radical scavenging method. Then, the anti-inflammatory