7115-16-4

Basic information

• Product Name: 1-CHLORO-3-METHYL-ISOQUINOLINE
• Synonyms: 1-CHLORO-3-METHYL-ISOQUINOLINE ;Isoquinoline, 1-chloro-3-Methyl-
• CAS NO: 7115-16-4
• Molecular Formula: C₁₀H₈ClN
• Molecular Weight: 177.63022
• Mol File: 7115-16-4.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 299.4 °C at 760 mmHg
• Flash Point: 163.1 °C
• Appearance: /
• Density: 1.225 g/cm³
• Vapor Pressure: 0.00213mmHg at 25°C
• Refractive Index: 1.634
• CAS DataBase Reference: 1-CHLORO-3-METHYL-ISOQUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-CHLORO-3-METHYL-ISOQUINOLINE(7115-16-4)
• EPA Substance Registry System: 1-CHLORO-3-METHYL-ISOQUINOLINE(7115-16-4)

Safety Data

• Hazardous Substances Data: 7115-16-4(Hazardous Substances Data)

Usage

General Description

1-Chloro-3-methyl-isoquinoline is a chemical compound with the formula C10H8ClN. It is a heterocyclic aromatic compound containing a chlorine atom and a methyl group attached to an isoquinoline ring structure. This chemical is used in the synthesis of pharmaceutical compounds and has shown potential as an antimicrobial agent. It has also been studied for its potential antitumor activity. Additionally, 1-chloro-3-methyl-isoquinoline has been investigated for its use in organic light-emitting diodes (OLEDs) and other optoelectronic applications due to its unique electronic and photophysical properties. Overall, this compound has demonstrated potential for diverse applications in the fields of medicine, materials science, and organic electronics.

InChI:InChI=1/C10H8ClN/c1-7-6-8-4-2-3-5-9(8)10(11)12-7/h2-6H,1H3

Upstream product

• 7114-80-9 3-methylisoquinolone 
• 7114-80-9 3-methylisoquinolin-1-ol 
• 10025-87-3 trichlorophosphate 
• 85-44-9 phthalic anhydride 
• 5423-95-0 4-hydroxy-3-methyl-2H-isoquinolin-1-one 
• 14380-86-0 ethyl 2-(1,3-dioxoisoindolin-2-yl)propanoate 
• 29539-21-7 3-methylisocoumarin 
• 14548-00-6 3-methylisoquinoline N-oxide 
• 1125-80-0 3-methylisoquinoline 
• 63870-81-5 1-ethoxy-3-methylisoquinoline 
• 825-60-5 benzimidic acid ethyl ester 

Downstream Products

• 1125-80-0 3-methylisoquinoline 
• 7114-80-9 3-methylisoquinolin-1-ol 
• 77619-94-4 3-(3-methylisoquinolin-1-yl)isobenzofuran-1(3H)-one 
• 129881-56-7 3-methyl-2-<(3-oxo-1,3-dihydroisobenzofuran-1-yl)carbonyl>isoquinolin-1(2H)-one 
• 27107-35-3 5-Methyl-s-triazolo<3,4-a>isochinolin 
• 1380213-42-2 C₂₃H₂₅N₃O₂ 

Relevant articles and documents

Synthesis of rhodium(III)-catalyzed isoquinoline derivatives from allyl carbonates and benzimidates with hydrogen evolution

A novel Rh(iii)-catalyzed cascade C-H activation/cyclization approach to access isoquinoline derivatives from benzimidates and available allyl carbonates with the liberation of H2 has been realized. Allyl carbonates were first used as a versati

Regioselective Chlorination of Quinoline N-Oxides and Isoquinoline N-Oxides Using PPh3/Cl3CCN

A novel method for the regioselective C2-chlorination of heterocyclic N-oxides has been developed. PPh3/Cl3CCN were used as chlorinating reagents and the desired N-heterocyclic chlorides were obtained smoothly in satisfactory yields. The reactions proceeded in a highly efficient and selective manner across a broad range of substrates demonstrating excellent functional group tolerance. In addition, this chlorination reaction can be used for the modification of N-heterocyclic scaffolds of appealing ligands and pharmaceuticals.

HEPATITIS C VIRUS INHIBITORS

Hepatitis C virus inhibitors are disclosed having the general formula:(I) wherein R1, R2, R3, R', B, Y and X are described in the description. Compositions comprising the compounds and methods for using the compounds toinhibit HCV are also disclosed.