7120-02-7

Basic information

• Product Name: N-[4-(4-CHLORO-PHENYL)-THIAZOL-2-YL]-GUANIDINE
• Synonyms: N-[4-(4-CHLORO-PHENYL)-THIAZOL-2-YL]-GUANIDINE;N-[4-(4-CHLOROPHENYL)-1,3-THIAZOL-2-YL]GUANIDINE;2-[4-(4-chlorophenyl)-1,3-thiazol-2-yl]guanidine;2-[4-(4-chlorophenyl)-2-thiazolyl]guanidine;2-[4-(4-chlorophenyl)thiazol-2-yl]guanidine;5T-0906;7M-619S
• CAS NO: 7120-02-7
• Molecular Formula: C₁₀H₉ClN₄S
• Molecular Weight: 252.72
• Mol File: 7120-02-7.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-[4-(4-CHLORO-PHENYL)-THIAZOL-2-YL]-GUANIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-[4-(4-CHLORO-PHENYL)-THIAZOL-2-YL]-GUANIDINE(7120-02-7)
• EPA Substance Registry System: N-[4-(4-CHLORO-PHENYL)-THIAZOL-2-YL]-GUANIDINE(7120-02-7)

Safety Data

• Hazardous Substances Data: 7120-02-7(Hazardous Substances Data)

Upstream product

• 2114-02-5 amidinothiocarbamide 
• 536-38-9 4-chlorobenzoylmethyl bromide 
• 99-91-2 para-chloroacetophenone 

Downstream Products

• 92423-67-1 2-[4-(4-chloro-phenyl)-thiazol-2-ylamino]-6-methyl-3H-pyrimidin-4-one 
• 92435-42-2 [4-(4-chloro-phenyl)-thiazol-2-yl]-(4,6-dimethyl-pyrimidin-2-yl)-amine 

Relevant articles and documents

Method for synthesizing 2-guanidinothiazole compound by one-pot process

According to the invention, a substituted methyl ketone compound is innovatively used as a raw material, amidinothiourea is added into an alcohol solvent under the conditions of halogeno salt MX and Oxone, and a one-pot process one-step reaction is carried out to obtain the target 2-guanidinothiazole compound. Common methyl ketone is used for replacing an alpha-halogenated carbonyl compound whichis high in price and toxicity, MX which is low in price and easy to obtain is used as a halogen source, the method is novel, raw materials and reagents are cheap, reaction conditions are mild, and operation is easy and convenient, therefore low-cost, convenient and rapid synthesis of the 2-guanidinothiazole compound is achieved.