713145-08-5

Basic information

• Product Name: 3-{6-[4-(2-cyano-ethyl)-piperazin-1-yl]-[1,7]naphthyridin-8-yl}-benzonitrile
• Synonyms: 3-{6-[4-(2-cyano-ethyl)-piperazin-1-yl]-[1,7]naphthyridin-8-yl}-benzonitrile
• CAS NO: 713145-08-5
• Molecular Weight: 404.902
• Mol File: 713145-08-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-{6-[4-(2-cyano-ethyl)-piperazin-1-yl]-[1,7]naphthyridin-8-yl}-benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-{6-[4-(2-cyano-ethyl)-piperazin-1-yl]-[1,7]naphthyridin-8-yl}-benzonitrile(713145-08-5)
• EPA Substance Registry System: 3-{6-[4-(2-cyano-ethyl)-piperazin-1-yl]-[1,7]naphthyridin-8-yl}-benzonitrile(713145-08-5)

Safety Data

• Hazardous Substances Data: 713145-08-5(Hazardous Substances Data)

Upstream product

• 524734-41-6 6-trifluoromethanesulfonyl-8-(3-cyanophenyl)-1,7-naphthyridine 
• 34064-86-3 3-piperazin-1-yl-propionitrile 

Relevant articles and documents

[1,7]NAPHTHYRIDINES AS PDE4 INHIBITORS

Compounds of Formula (I) in free or salt form, wherein R1, R2 and R3 have the meanings as indicated in the specification, are useful for treating conditions mediated by of phosphodiesterase type 4 or the down-regulation or inhibition of TNF-α release, particularly obstructive or inflammatory airways diseases. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.