7145-82-6 Usage
Description
1-IODO-2,4,5-TRICHLOROBENZENE, also known as 1,2,4-Trichloro-5-iodobenzene, is an organic compound with the molecular formula C6H2Cl3I. It is characterized by the presence of three chlorine atoms at the 2nd, 4th, and 5th positions, and an iodine atom at the 1st position on a benzene ring. 1-IODO-2,4,5-TRICHLOROBENZENE is known for its unique chemical properties and reactivity, making it a valuable intermediate in various chemical reactions and synthesis processes.
Uses
1. Used in Chemical Synthesis:
1-IODO-2,4,5-TRICHLOROBENZENE is used as a reagent for the synthesis of sterically hindered polychlorinated biphenyls (PCBs). 1-IODO-2,4,5-TRICHLOROBENZENE's unique structure allows it to participate in various chemical reactions, such as Suzuki and Ullmann reactions, which are crucial for the formation of these PCBs. These PCBs have a wide range of applications, including as additives in the manufacturing of plastics, lubricants, and other industrial materials.
2. Used in Pharmaceutical Industry:
1-IODO-2,4,5-TRICHLOROBENZENE can be utilized as a building block or intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and reactivity make it a valuable component in the development of new drugs and therapeutic agents.
3. Used in Research and Development:
Due to its unique chemical properties, 1-IODO-2,4,5-TRICHLOROBENZENE is often used in research and development for the study of chemical reactions, mechanisms, and the development of new synthetic methods. It can also be employed as a reference compound for the calibration of analytical instruments and techniques.
4. Used in Material Science:
1-IODO-2,4,5-TRICHLOROBENZENE's unique structure and properties make it a potential candidate for the development of new materials with specific characteristics, such as high thermal stability, chemical resistance, or electronic properties. It can be used in the synthesis of novel polymers, coatings, or other advanced materials for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 7145-82-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,1,4 and 5 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 7145-82:
(6*7)+(5*1)+(4*4)+(3*5)+(2*8)+(1*2)=96
96 % 10 = 6
So 7145-82-6 is a valid CAS Registry Number.
InChI:InChI=1/C6H2Cl3I/c7-3-1-5(9)6(10)2-4(3)8/h1-2H
7145-82-6Relevant articles and documents
Dehalogenation of o-dihalogen substituted arenes and α,α′-dihalogen substituted o-xylenes with lanthanum metal
Nishiyama, Yutaka,Kawabata, Hiroshi,Nishino, Toshiki,Hashimoto, Kouji,Sonoda, Noboru
, p. 6609 - 6614 (2007/10/03)
It was found that lanthanum metal caused the dehalogenation of o-dihalogen substituted arenes and α,α′-dihalogen substituted o-xylenes to generate the corresponding benzynes and o-quinodimethanes. When o-dihalogen substituted arenes were allowed to react with lanthanum metal in the presence of dienes, the Diels-Alder products between benzyne and dienes were formed in moderate to good yields. Similarly, the Diels-Alder adducts of o-quinodimethane with dienophiles were obtained, in the reaction of α,α′-dibromo-o-xylenes with lanthanum metal in the presence of dienophiles.
Nucleophilic Displacement in Polyhalogenoaromatic Compounds. Part 11. Kinetics of Protiodeiodination of Iodoarenes in Dimethyl Sulphoxide-Methanol
Bolton, Roger,Moore, Clive,Sandall, John P.B.
, p. 1593 - 1598 (2007/10/02)
The rates of methoxide-ion induced protiodeiodination of a number of polychloroiodobenzenes and their derivatives have been measured in dimethyl sulphoxide-methanol (9:1 v/v; 323.2 K).The true reagent under these conditions appears to be the dimethyl sulphoxide anion, and the rates of reaction in some cases appear to approach that expected of a diffusion controlled process.This corresponds to a major decrease in the efficacy of further activating substituents in the aromatic system, altough deactivating groups such as p-OMe still show large effects.Chlorine promotes protiodeiodination in the order of efficiency o-Cl > m-Cl > p-Cl; the trifluoromethyl group activates displacement in the order o-CF3 > p-CF3 > m-CF3, although with much less difference between isomeric sites. o-Nitro-groups promote protiodeiodination whereas the p-nitro-group encourages methoxydeiodination.No evidence of methoxydeiodination was found in attack of the polychloroiodobenzenes, although the rates of methoxydechlorination of the corresponding polychlorobenzenes suggest that in some cases this might occur.Evidence rejecting the possible SRN1 mechanism and supporting nucleophilic attack by a carbanionic species upon iodine is presented.
