7147-74-2 Usage
Description
1-(1H-benzoimidazol-2-yl)pentane-1,2,3,4,5-pentol, commonly known as pentamidine, is a synthetic compound with significant antiprotozoal and antibacterial properties. It is characterized by its ability to inhibit the synthesis of DNA, RNA, and proteins in microorganisms, leading to their death. Pentamidine is recognized for its potent and broad-spectrum antimicrobial activity, making it a crucial agent in the medical field. Despite its effectiveness, it is also known to have various side effects and is generally used as a last resort for severe infections when other treatments have been exhausted.
Uses
Used in Pharmaceutical Applications:
1-(1H-benzoimidazol-2-yl)pentane-1,2,3,4,5-pentol is used as an antiprotozoal agent for the treatment of Pneumocystis jiroveci pneumonia, a severe lung infection that primarily affects immunocompromised individuals. Its application is based on its ability to effectively target and eliminate the causative pathogen, Pneumocystis jiroveci.
Used in Treatment of Parasitic Infections:
In the field of parasitology, 1-(1H-benzoimidazol-2-yl)pentane-1,2,3,4,5-pentol is used as an antiparasitic agent for the treatment of leishmaniasis, a disease caused by protozoan parasites from the genus Leishmania. Pentamidine's potent activity against these parasites makes it a valuable tool in managing and treating leishmaniasis.
Used in Trypanosomiasis Treatment:
1-(1H-benzoimidazol-2-yl)pentane-1,2,3,4,5-pentol is also used as an antiprotozoal agent for the treatment of African trypanosomiasis, also known as sleeping sickness. This disease is caused by the parasitic protozoa Trypanosoma brucei and is transmitted through the bite of an infected tsetse fly. Pentamidine's effectiveness in inhibiting the growth and proliferation of the parasite makes it a critical component in the treatment of this life-threatening condition.
Used in Antimicrobial Applications:
In the broader medical field, 1-(1H-benzoimidazol-2-yl)pentane-1,2,3,4,5-pentol is used as a broad-spectrum antimicrobial agent. Its ability to target a wide range of pathogens, including bacteria and protozoa, makes it a valuable asset in the treatment of various severe infections, particularly when other treatment options have proven ineffective.
Check Digit Verification of cas no
The CAS Registry Mumber 7147-74-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,1,4 and 7 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 7147-74:
(6*7)+(5*1)+(4*4)+(3*7)+(2*7)+(1*4)=102
102 % 10 = 2
So 7147-74-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H16N2O5/c15-5-8(16)9(17)10(18)11(19)12-13-6-3-1-2-4-7(6)14-12/h1-4,8-11,15-19H,5H2,(H,13,14)
