71494-99-0

Basic information

• Product Name: Benzeneacetonitrile, N-oxide
• CAS NO: 71494-99-0
• Molecular Formula: C8H7NO
• Molecular Weight: 133.15
• Mol File: 71494-99-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzeneacetonitrile, N-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetonitrile, N-oxide(71494-99-0)
• EPA Substance Registry System: Benzeneacetonitrile, N-oxide(71494-99-0)

Safety Data

• Hazardous Substances Data: 71494-99-0(Hazardous Substances Data)

Upstream product

• 122-78-1 phenylacetaldehyde 
• 6125-24-2 2-Phenylnitroethane 

Downstream Products

• 264607-24-1 3-benzyl-5-phenyl-4,5-dihydroisoxazole 
• 1034982-00-7 N-benzyl-2-(3-benzylisoxazol-5-yl)-4-methylthiazole-5-carboxamide 
• 5115-71-9 C₁₄H₁₈NO₉S₂^(1-)*K⁽¹⁺⁾ 
• 101960-39-8 5-amino-6-phenylhexa-1,4-dien-3-one 
• 101960-41-2 5,6-dihydro-2-benzyl-4-pyridone 
• 101960-36-5 spiro<4,5-dihydro-3-benzylisoxazole-5,1'-cyclopropane> 
• 130718-54-6 Acetic acid (2R,3R,4S,5R,6R)-4,5-diacetoxy-6-acetoxymethyl-2-(N-hydroxy-2-phenyl-acetimidoylsulfanyl)-tetrahydro-pyran-3-yl ester 

Relevant articles and documents

One-pot synthesis of isoxazolines from aldehydes catalyzed by iodobenzene

A convenient one-pot, three-step procedure for the synthesis of isoxazolines starting from aldehydes has been developed involving catalytic cycloaddition between nitrile oxides and alkenes, in which iodobenzene is used as the catalyst for the in situ generation of a hypervalent iodine intermediate. In this approach, the aldehydes are first transformed with hydroxylamine sulfate into aldoximes, which are then oxidized to nitrile oxides by the in situ generated hypervalent iodine intermediate; finally, a 1,3-dipolar cycloaddition between the nitrile oxides and alkenes occurs to provide the isoxazolines in moderate to good yields.