71590-08-4

Basic information

• Product Name: METHYL 5-METHOXY-ISOPHTHALATE
• Synonyms: METHYL 5-METHOXY-ISOPHTHALATE;3-METHOXYCARBONYL-5-METHOXYBENZOIC ACID;3-METHOXYCARBONYL-5-METHOXYBENZOIC ACIDMETHYL 5-METHOXY-ISOPHTHALATE;METHYL 3-(HYDROXYMETHYL)-5-METHOXYBENZOATE
• CAS NO: 71590-08-4
• Molecular Formula: C₁₀H₁₀O₅
• Molecular Weight: 210.18
• EINECS: 200-258-5
• Mol File: 71590-08-4.mol
• Article Data: 10

Chemical Properties

• Melting Point: 165-166 °C
• Boiling Point: 383.4 °C at 760 mmHg
• Flash Point: 153.7 °C
• Appearance: /
• Density: 1.282 g/cm³
• Vapor Pressure: 1.46E-06mmHg at 25°C
• Refractive Index: 1.542
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 3.71±0.10(Predicted)
• CAS DataBase Reference: METHYL 5-METHOXY-ISOPHTHALATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 5-METHOXY-ISOPHTHALATE(71590-08-4)
• EPA Substance Registry System: METHYL 5-METHOXY-ISOPHTHALATE(71590-08-4)

Safety Data

• Hazardous Substances Data: 71590-08-4(Hazardous Substances Data)

Usage

General Description

Methyl 5-methoxy-isophthalate is a chemical compound primarily used in the production of ballpoint pen inks and dye intermediates. It is a derivative of isophthalic acid, containing a methyl and a methoxy group on the 5th and 3rd carbon atoms, respectively. METHYL 5-METHOXY-ISOPHTHALATE is commonly used in the synthesis of polyesters, which have applications in various industries such as textiles, packaging, and automotive. It is also employed in the formulation of coating and adhesive products. Methyl 5-methoxy-isophthalate is considered to be relatively low in toxicity and poses minimal environmental risk when handled and disposed of properly.

InChI:InChI=1/C10H10O5/c1-14-8-4-6(9(11)12)3-7(5-8)10(13)15-2/h3-5H,1-2H3,(H,11,12)

Upstream product

• 20319-44-2 dimethyl 5-methoxyisophthalate 
• 618-83-7 5-Hydroxyisophthalic acid 
• 13036-02-7 Dimethyl 5-hydroxyisophthalate 

Downstream Products

• 367519-84-4 3-hydroxymethyl-5-methoxy-benzoic acid methyl ester 
• 71590-09-5 methyl 3-(chlorocarbonyl)-5-methoxybenzoate 
• 468060-85-7 3-hydroxy-5-(6-methyl-4-oxo-4H-chromen-2-yl)-benzoic acid methyl ester 
• 468060-84-6 3-methoxy-5-(6-methyl-4-oxo-4H-chromen-2-yl)-benzoic acid methyl ester 
• 742101-54-8 2-acetyl-4-methylphenyl methyl 5-methoxyisophthalate 
• 742101-59-3 methyl 3-[3-(2-hydroxy-5-methylphenyl)-3-oxopropanoyl]-5-methoxybenzoate 
• 69026-10-4 methyl 5-formyl-3-methoxybenzoate 
• 367519-88-8 5-formyl-3-methoxybenzoic acid 
• 1257657-26-3 (S)-7-(allyl-tert-butoxycarbonylamino)-7-[2-(3-methoxy-5-vinylbenzyloxy)-phenylcarbamoyl]-heptanoic acid methyl ester 
• 1257657-34-3 N-(2-tert-butoxycarbonylamino-phenyl)-5-methoxy-isophthalamic acid methyl ester 
• 1257657-35-4 tert-butyl 2-(3-formyl-5-methoxybenzamido)phenylcarbamate 

Relevant articles and documents

Cobalt(III)-Catalyzed Construction of Benzofurans, Benzofuranones and One-Pot Orthogonal C?H Functionalizations to Access Polysubstituted Benzofurans

Benzofuran and benzofuranone derivatives have been synthesized through exclusive 5-exo-dig intramolecular hydroarylation using the amide-directed, cost-effective, high-valent Cp*CoIII-catalytic system. Challenging one-pot, orthogonal C?H functionalizations using two different electrophiles are also reported to afford polysubstituted benzofurans. Several valuable functional group interconversions along with removal of the amide directing group provide a route to access several diversely functionalized benzofurans. The mechanistic study suggests a reversible cobaltation step is operative here. (Figure presented.).

Hydroxylated 1,2,4-oxadiazole benzoic acid compounds, composistions thereof and the use for nonsense suppression

Novel hydroxylated 1,2,4-oxadiazole benzoic acid compounds, methods of using and pharmaceutical compositions comprising a hydroxylated 1,2,4-oxadiazole benzoic acid derivative are disclosed. The methods include methods of treating or preventing a disease

Inhibitors of the FEZ-1 metallo-β-lactamase

Metallo-β-lactamases (MBLs) catalyze the hydrolysis of β-lactams including penicillins, cephalosporins and carbapenems. Starting from benzohydroxamic acid (1) structure-activity studies led to the identification of selective inhibitors of the FEZ-1 MBL, e.g., 2,5-substituted benzophenone hydroxamic acid 17 has a Ki of 6.1 ± 0.7 μM against the FEZ-1 MBL but does not significantly inhibit the IMP-1, BcII, CphA or L1 MBLs.