716-17-6 Usage
Description
(2R)-3-(6-aminopurin-9-yl)propane-1,2-diol is a purine derivative that is structurally related to adenine, a nucleobase present in DNA and RNA. This chemical compound features a purine base with a propylene glycol chain attached, playing a significant role in the structure and function of nucleic acids, which is essential for the storage and transfer of genetic information.
Uses
Used in Biochemistry and Molecular Biology Research:
(2R)-3-(6-aminopurin-9-yl)propane-1,2-diol serves as a research tool in biochemistry and molecular biology, aiding scientists in understanding the mechanisms of nucleic acid function and the role of purines in biological processes.
Used in the Synthesis of Nucleoside Analogs:
(2R)-3-(6-aminopurin-9-yl)propane-1,2-diol is utilized in the synthesis of nucleoside analogs, which are structurally similar to natural nucleosides but differ in specific functional groups. Nucleoside analogs have applications in various fields, including medicine, where they can be used as antiviral or anticancer agents due to their ability to interfere with nucleic acid synthesis and function.
Check Digit Verification of cas no
The CAS Registry Mumber 716-17-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,1 and 6 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 716-17:
(5*7)+(4*1)+(3*6)+(2*1)+(1*7)=66
66 % 10 = 6
So 716-17-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H11N5O2/c9-7-6-8(11-3-10-7)13(4-12-6)1-5(15)2-14/h3-5,14-15H,1-2H2,(H2,9,10,11)
716-17-6Relevant articles and documents
8-Bromo-9-alkyl adenine derivatives as tools for developing new adenosine A2A and A2B receptors ligands
Lambertucci, Catia,Antonini, Ippolito,Buccioni, Michela,Dal Ben, Diego,Kachare, Dhuldeo D.,Volpini, Rosaria,Klotz, Karl-Norbert,Cristalli, Gloria
experimental part, p. 2812 - 2822 (2009/09/08)
Importance of making available selective adenosine receptor antagonists is boosted by recent findings of adenosine involvement in many CNS dysfunctions. In the present work a series of 8-bromo-9-alkyl adenines are prepared and fully characterized in radio
Reaction of 8-Substituted Adenines with Glycidol
Ratsino, E. V.,Radchenko, S. I.
, p. 273 - 275 (2007/10/03)
The regioselectivity of isomer formation in the reaction of 8-substituted adenines with glycidol depends on steric factors of substituents.The compounds prepared were tested for immunostimulating activity.
EASY ALKYLATION OF PURINE BASES BY SOLID-LIQUID PHASE TRANSFER CATALYSIS WITHOUT SOLVENT. STRUCTURAL ANALYSIS BY 2D HETERONUCLEAR 1H 13C CORRELATED NMR SPECTROSCOPY
Platzer, Nicole,Galons, Herve,Bensaid, Younes,Miocque, Marcel,Bram, Georges
, p. 2101 - 2108 (2007/10/02)
Solid-liquid PTC without added organic solvent promotes alkylation of purine derivatives leading in particular to an efficient synthesis of the antiviral DHPA.The location of the substituent on the ring was determined by analysis of coupling interactions
