716-43-8

Basic information

• Product Name: methyl 2-(2-methoxy-2-oxoethyl)benzenecarboxylate
• Synonyms: methyl 2-(2-methoxy-2-oxoethyl)benzenecarboxylate
• CAS NO: 716-43-8
• Molecular Formula: C₁₁H₁₂O₄
• Molecular Weight: 208.22
• Mol File: 716-43-8.mol
• Article Data: 32

Chemical Properties

• Melting Point: 54.8-56.2 °C
• Boiling Point: 303.5°C at 760 mmHg
• Flash Point: 148.9°C
• Appearance: /
• Density: 1.155g/cm³
• Vapor Pressure: 0.000924mmHg at 25°C
• Refractive Index: 1.511
• CAS DataBase Reference: methyl 2-(2-methoxy-2-oxoethyl)benzenecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-(2-methoxy-2-oxoethyl)benzenecarboxylate(716-43-8)
• EPA Substance Registry System: methyl 2-(2-methoxy-2-oxoethyl)benzenecarboxylate(716-43-8)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 716-43-8(Hazardous Substances Data)

Usage

General Description

Methyl 2-(2-methoxy-2-oxoethyl)benzenecarboxylate is a chemical compound with the molecular formula C11H12O5. It is an ester with a benzene ring and a carboxylate group, as well as a methoxy and oxoethyl substituents. This chemical is commonly used as a flavoring agent and fragrance ingredient in the food and cosmetic industries. It has a sweet, floral, and fruity odor and is often used in perfumes, colognes, and other scented products. Additionally, it has potential applications in pharmaceuticals and organic synthesis due to its unique chemical structure and properties.

InChI:InChI=1/C11H12O4/c1-14-10(12)7-8-5-3-4-6-9(8)11(13)15-2/h3-6H,7H2,1-2H3

Upstream product

• 186581-53-3 diazomethane 
• 89-51-0 Homophthalic acid 
• 67-56-1 methanol 
• 85-44-9 phthalic anhydride 
• 90271-74-2 1,3-bis(diazo)indan-2-one 
• 147688-73-1 1-diazoindan-2,3-dione 
• 147688-74-2 1-diazo-3,3-dimethoxyindan-2-one 
• 703-59-3 homophthalic anhydride 
• 39650-82-3 2,2-dimethoxy-1-methylpyrrolidine 
• 1807-49-4 2-diazo-indan-1,3-dione 
• 88-67-5 2-Iodobenzoic acid 
• 141-97-9 ethyl acetoacetate 
• 73927-93-2 (C₄H₉)3SnOOCC₆H₄I-2 
• 74-88-4 methyl iodide 

Downstream Products

• 167541-51-7 2-(1-methoxycarbonyl-2,2-diphenyl-vinyl)-benzoic acid 
• 437652-17-0 methyl β-(3,4-methylenedioxyphenyl)-α-(2-carboxyphenyl)acrylate 
• 71568-89-3 2-(2-methoxycarbonyl-phenyl)-3-oxo-propionic acid methyl ester 
• 14736-49-3 2-(2-(methoxycarbonyl)phenyl)acetic acid 
• 10479-70-6 (+/-)-(trans-2-carboxy-cyclohexyl)-acetic acid 
• 10479-70-6 (+/-)-(cis-2-carboxy-cyclohexyl)-acetic acid 
• 612-35-1 2-Benzylbenzoic acid 
• 2897-86-1 methyl ester of 2-(2-carboxyphenyl)-3-phenylacrylic acid 
• 952015-61-1 2-(1-methoxycarbonyl-2-methyl-propenyl)-benzoic acid 
• 19916-47-3 o-Methylsulfonylacetylphenylessigsaeure 
• 16061-73-7 3-(2-cyanomethylphenyl)propionitrile 
• 89-51-0 Homophthalic acid 
• 167541-86-8 methyl ester of 2-(2-carboxyphenyl)-3-(2-furyl)acrylic acid 
• 93630-96-7 2-methoxycarbonyl-α-(methoxycarbonyl)-β-tryptaminyl-styrene 

Relevant articles and documents

4-benzylideneisoquinoline-1,3(2H,4H)-diones as tyrosyl DNA phosphodiesterase 2 (TDP2) inhibitors

Tyrosyl-DNA phosphodiesterase 2 (TDP2) repairs topoisomerase II (Top2) mediated DNA damages, including double-strand breaks (DSBs) that underpin the anticancer mechanism of clinical Top2 poisons such as etoposide (ETP). Inhibition of TDP2 could sensitize

Efficient flow fischer esterification of carboxylic acids with alcohols using sulfonic acid-functionalized silica as supported catalyst

Flow Fischer esterification of carboxylic acids using hydroxy-substituted sulfonic acid-functionalized silica (HOSAS) packed into a stainless steel column reactor was investigated. HO-SAS well catalyzed flow esterification of long chain carboxylic acids with methanol within 3min of residence time at 110°C, and the methyl esters were quantitatively obtained. The flow esterification protocol was applied to the synthesis of a variety of esters (19 examples) and scalable synthesis was also successful.