71856-95-6

Basic information

• Product Name: 3-Formylbenzophenone
• Synonyms: 3-Benzoylbenzaldehyde;3-Formylbenzophenone
• CAS NO: 71856-95-6
• Molecular Formula: C₁₄H₁₀O₂
• Molecular Weight: 0
• Mol File: 71856-95-6.mol
• Article Data: 20

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Formylbenzophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Formylbenzophenone(71856-95-6)
• EPA Substance Registry System: 3-Formylbenzophenone(71856-95-6)

Safety Data

• Hazardous Substances Data: 71856-95-6(Hazardous Substances Data)

Upstream product

• 22071-24-5 3-benzoylbenzyl bromide 
• 145695-60-9 3-Nitratomethylbenzophenone 
• 56338-25-1 [3-(hydroxymethyl)phenyl](phenyl)methanone 
• 72235-46-2 [3-(Dibromomethyl)phenyl]phenylmethanone 
• 579-18-0 3-benzoylbenzoic acid 
• 203442-00-6 [3-(hydroxymethyl)phenyl](phenyl)methanol 
• 643-65-2 3-methyl benzophenone 
• 52010-96-5 3-(hydroxy(phenyl)methyl)benzaldehyde 
• 696-41-3 m-iodobenzaldehyde 
• 98-88-4 benzoyl chloride 
• 87199-16-4 3-Formylphenylboronic acid 
• 65-85-0 benzoic acid 
• 17789-14-9 3-(1,3-dioxolan-2-yl)-phenylbromide 
• 6919-61-5 N-methoxy-N-methylbenzamide 

Downstream Products

• 96251-93-3 (E)-ethyl 3-(3-benzoylphenyl)acrylate 
• 145695-51-8 4-(3-Benzoyl-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diisopropyl ester 
• 145695-49-4 4-(3-Benzoyl-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diallyl ester 
• 145695-57-4 4-(3-Benzoyl-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid bis-(2-methoxy-ethyl) ester 
• 145695-54-1 4-(3-Benzoyl-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid diethyl ester 
• 145695-53-0 4-(3-Benzoyl-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-methyl ester 
• 145695-48-3 4-(3-Benzoyl-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-allyl ester 5-ethyl ester 
• 145695-56-3 4-(3-Benzoyl-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-ethyl ester 5-(2-methoxy-ethyl) ester 
• 145695-52-9 dimethyl 1,4-dihydro-2,6-dimethyl-4-(3-benzoylphenyl)-3,5-dicarboxylate 
• 145695-50-7 4-(3-Benzoyl-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-isopropyl ester 5-methyl ester 
• 145695-58-5 4-(3-Benzoyl-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-methyl ester 5-prop-2-ynyl ester 
• 145695-47-2 4-(3-Benzoyl-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-allyl ester 5-methyl ester 
• 145695-59-6 4-(3-Benzoyl-phenyl)-2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarboxylic acid 3-methyl ester 5-(2-piperidin-1-yl-ethyl) ester 
• 863030-40-4 3-(α-hydroxy-4'-methylbenzyl)benzophenone 

Relevant articles and documents

Cobalt(ii)-catalyzed benzylic oxidations with potassium persulfate in TFA/TFAA

A cobalt-catalyzed C(sp3)-H oxygenation reaction to furnish aldehyde was herein reported. This transformation demonstrated high chemo-selectivity, and tolerated various methylarenes bearing electron-withdrawing substituents. This reaction provided rapid access to diverse aldehydes form methylarenes. Notably, TFA/TFAA was used for the first time as a mixed solvent in cobalt-catalyzed oxygenation of benzylic methylenes.

CO2-Catalyzed oxidation of benzylic and allylic alcohols with DMSO

CO2-catalyzed transition-metal-free oxidation of alcohols has been achieved. Earlier, several methodologies have been explored for alcohol oxidations based on transition-metal catalysts. However, owing to the cheaper price, easy separation and nontoxicity, transition-metal-free systems are in high demand to the pharmaceutical industries. For this reason, various primary and secondary alcohols have been selectively oxidized to the corresponding carbonyl compounds using CO2 as a catalyst in the presence of different functional groups such as nitrile, nitro, aldehyde, ester, halogen, ether, and so on. At the end, transition-metal-free syntheses of pharmaceuticals have also been achieved. Finally, the role of CO2 has been investigated in detail, and the mechanism is proposed on the basis of experiments and DFT calculations.

Development of a Rhodium(II)-Catalyzed Chemoselective C(sp3)-H Oxygenation

We report the first example of RhII-catalyzed chemoselective double C(sp3)-H oxygenation, which can directly transform various toluene derivatives into highly valuable aromatic aldehydes with great chemoselectivity and practicality. The critical combination of catalyst Rh(OAc)2, oxidant Selectfluor, and solvents of TFA/TFAA promises the successful delivery of the oxidation with satisfactory yields. A possible mechanism involving a unique carbene-Rh complex is proposed, and has been supported by both experiments and theoretical calculations.