720-82-1 Usage
Description
H-ALA-BETANA, also known as L-alanine-2-naphthylamide, is an L-alanine derivative formed by the formal condensation of the carboxy group of L-alanine with the amino group of 2-naphthylamine. It is a white crystalline solid and has been used in various applications due to its unique properties.
Uses
Used in Analytical Chemistry:
H-ALA-BETANA is used as a chiral derivatizing reagent for the enantiomeric separation of amino acids and other chiral compounds. It aids in the analysis and determination of enantiomers by enhancing their resolution and selectivity during chromatographic separations.
Used in Pharmaceutical Industry:
H-ALA-BETANA is used as a building block in the synthesis of various pharmaceutical compounds, including drugs and drug candidates. Its unique structure allows for the development of new molecules with potential therapeutic applications.
Used in Research and Development:
H-ALA-BETANA is utilized in research and development for the study of enzyme substrate specificity, enzyme inhibition, and the development of new analytical methods for the detection and quantification of chiral compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 720-82-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,2 and 0 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 720-82:
(5*7)+(4*2)+(3*0)+(2*8)+(1*2)=61
61 % 10 = 1
So 720-82-1 is a valid CAS Registry Number.
InChI:InChI=1/C13H14N2O/c1-9(14)13(16)15-12-7-6-10-4-2-3-5-11(10)8-12/h2-9H,14H2,1H3,(H,15,16)
720-82-1Relevant articles and documents
New chiral stationary phases for liquid chromatography based on small molecules: Development, enantioresolution evaluation and chiral recognition mechanisms
Phyo, Ye' Zaw,Teixeira, Joana,Tiritan, Maria Elizabeth,Cravo, Sara,Palmeira, Andreia,Gales, Luís,Silva, Artur M.S.,Pinto, Madalena M.M.,Kijjoa, Anake,Fernandes, Carla
, p. 81 - 97 (2019/11/28)
Recently, we reported the development of new chiral stationary phases (CSPs) for liquid chromatography (LC) based on chiral derivatives of xanthones (CDXs). Based on the most promising CDX selectors, 12 new CSPs were successfully prepared starting from suitable functionalized small molecules including xanthone and benzophenone derivatives. The chiral selectors comprising one, two, three, or four chiral moieties were covalently bonded to a chromatographic support and further packed into LC stainless-steel columns (150?×?2.1?mm I.D.). The enantioselective performance of the new CSPs was evaluated by LC using different classes of chiral compounds. Specificity for enantioseparation of some CDXs was observed in the evaluation of the new CSPs. Besides, assessment of chiral recognition mechanisms was performed by computational studies using molecular docking approach, which are in accordance with the chromatographic parameters. X-Ray analysis was used to establish a chiral selector 3D structure.
