72081-17-5

Basic information

• Product Name: (3,4-dihydro-2H-pyran-6-yl)Methanol
• Synonyms: (3,4-dihydro-2H-pyran-6-yl)Methanol;3,4-dihydro-2H-Pyran-6-methanol
• CAS NO: 72081-17-5
• Molecular Formula: C₆H₁₀O₂
• Molecular Weight: 114.1424
• Mol File: 72081-17-5.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: (3,4-dihydro-2H-pyran-6-yl)Methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (3,4-dihydro-2H-pyran-6-yl)Methanol(72081-17-5)
• EPA Substance Registry System: (3,4-dihydro-2H-pyran-6-yl)Methanol(72081-17-5)

Safety Data

• Hazardous Substances Data: 72081-17-5(Hazardous Substances Data)

Usage

General Description

(3,4-dihydro-2H-pyran-6-yl)Methanol, also known as tetrahydropyran-4-ol, is a chemical compound with the molecular formula C6H12O2. It is a colorless liquid with a pleasant, fruity odor that is commonly used as a solvent in various industrial processes. (3,4-dihydro-2H-pyran-6-yl)Methanol is also utilized in the synthesis of pharmaceuticals, agrochemicals, and flavors. (3,4-dihydro-2H-pyran-6-yl)Methanol is considered to be relatively stable under normal conditions, but it can react with oxidizing agents and strong acids. Additionally, it may be harmful if swallowed, inhaled, or absorbed through the skin, and can cause irritation to the respiratory system and skin. Therefore, proper precautions should be taken when handling and using this chemical.

Upstream product

• 50-00-0 formaldehyd 
• 72081-15-3 6-lithio-3,4-dihydro-2H-pyran 
• 83505-61-7 ethyl 4,5-dihydropyran-2-carboxylate 
• 110-87-2 3,4-dihydro-2H-pyran 
• 5631-95-8 2,3-dichlorotetrahydro-2H-pyran 
• 31518-14-6 3,4-dihydro-2H-pyran-6-carboxylic acid 
• 31518-09-9 2-cyano-3-chlorotetrahydropyran 
• 26271-66-9 3,4-dihydro-2H-pyran-6-carbaldehyde 

Downstream Products

• 89429-82-3 6-benzyloxymethyl-3,4-dihydro-2H-pyran 
• 191600-86-9 6-Benzyloxy-5-oxo-hexanoic acid 
• 191600-88-1 (3S,8aS)-8a-Benzyloxymethyl-3-phenyl-2,3,8,8a-tetrahydro-oxazolo[3,2-a]pyridin-5-one 
• 191600-87-0 (3S,8aS)-8a-Benzyloxymethyl-3-phenyl-hexahydro-oxazolo[3,2-a]pyridin-5-one 
• 191600-89-2 (3S,8R,8aR)-8a-Benzyloxymethyl-8-hydroxy-3-phenyl-2,3,8,8a-tetrahydro-oxazolo[3,2-a]pyridin-5-one 
• 191600-90-5 (3S,6R,7R,8R,8aR)-8a-Benzyloxymethyl-6,7,8-trihydroxy-3-phenyl-hexahydro-oxazolo[3,2-a]pyridin-5-one 
• 191600-91-6 (3aR,5S,7aR,8R,8aR)-7a-Benzyloxymethyl-8-hydroxy-2,2-dimethyl-5-phenyl-hexahydro-1,3,7-trioxa-4a-aza-s-indacen-4-one 
• 191600-92-7 (3aS,6S,7S,7aR)-6-Benzyloxymethyl-5-((S)-2-hydroxy-1-phenyl-ethyl)-2,2-dimethyl-hexahydro-[1,3]dioxolo[4,5-c]pyridin-7-ol 
• 107757-68-6 dl-2-benzyloxymethyltetrahydropyran-3-one 
• 89429-83-4 hydroxy-3 benzyloxymethyl-2 tetrahydropyranne 
• 104954-99-6 dl-cis-2-benzyloxymethyltetrahydropyran-3-thiol 
• 104954-98-5 dl-S-(cis-2-benzyloxymethyltetrahydropyran-3-yl)thioacetate 
• 107757-73-3 Methanesulfonic acid (2S,3R)-2-benzyloxymethyl-tetrahydro-pyran-3-yl ester 
• 107757-66-4 dl-trans-2-benzyloxymethyltetrahydropyran-3-yl N-heptadecylcarbamate 

Relevant articles and documents

Stereoselective glycosylations using oxathiane spiroketal glycosyl donors

Novel oxathiane spiroketal donors have been synthesised and activated via an umpolung S-arylation strategy using 1,3,5-trimethoxybenzene and 1,3-dimethoxybenzene. The comparative reactivity of the resulting 2,4,6-trimethoxyphenyl (TMP)- and 2,4-dimethoxyp

Synthesis and comparative antibacterial activity of verdamicin C2 and C2a. A new oxidation of primary allylic azides in dihydro[2H]pyrans

(Chemical Equation Presented) A synthesis of verdamicin C2 and its congener C2a has been accomplished from sisomicin relying on a novel oxidative transformation of an allylic azide to the corresponding α,β- unsaturated aldehyde, and its stereocontrolled elaboration into the intended 5′ side chain of verdamicin C2 and C2a. In vitro antibacterial testing shows that both C6′ epimers in verdamicin C2 and C2a are equally active against a variety of bacterial strains. Oxidation of allylic primary azides, ethers, and esters of 2-substituted dihydro[2H]pyrans with SeO2 leads directly to the corresponding aldehydes.

Asymmetric synthesis of L-deoxymannojirimycin

Starting from dihydropyran 1, the chiral lactam 4 was rapidly obtained. Following unsaturation, highly diastereoselective allylic oxidation and dihydroxylation furnished lactam 7 from which the azasugar, L-deoxymannojirimycin, could be prepared.