7218-02-2

Basic information

• Product Name: 2,6-dimethylbenzene-1,4-diamine
• Synonyms: 2,6-dimethylbenzene-1,4-diamine;2,6-DIMETHYL-p-PHENYLENEDIAMINE;1,3-Dimethylbenzene-2,5-diamine;2,6-Dimethyl-1,4-phenylenediamine;m-Xylene-2,5-diamine;2,4-Dimethyl-1,3-benzenediamine;m-Xylene-2,4-diamine;4-Amino-2,6-dimethylaniline
• CAS NO: 7218-02-2
• Molecular Formula: C₈H₁₂N₂
• Molecular Weight: 136.19428
• EINECS: 230-608-3
• Mol File: 7218-02-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 282.2 °C at 760 mmHg
• Flash Point: 146.9 °C
• Appearance: /
• Density: 1.076 g/cm³
• Vapor Pressure: 0.0034mmHg at 25°C
• Refractive Index: 1.618
• Storage Temp.: 2-8°C
• PKA: 6.10±0.10(Predicted)
• CAS DataBase Reference: 2,6-dimethylbenzene-1,4-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-dimethylbenzene-1,4-diamine(7218-02-2)
• EPA Substance Registry System: 2,6-dimethylbenzene-1,4-diamine(7218-02-2)

Safety Data

• Hazardous Substances Data: 7218-02-2(Hazardous Substances Data)

Usage

General Description

2,6-dimethylbenzene-1,4-diamine, also known as 2,6-dimethylaniline or 1,3-dimethyl-2-phenylendiamine, is a chemical compound with the molecular formula C8H12N2. It is a colorless to pale yellow liquid at room temperature, and it is primarily used as an intermediate in the production of dyes and pigments. 2,6-dimethylbenzene-1,4-diamine is also used in the synthesis of pharmaceuticals and as a curing agent in epoxy resins. It is considered to be a hazardous chemical, with potential health effects including skin and eye irritation and respiratory issues. Due to its toxic and hazardous nature, proper handling and disposal procedures are required when working with this compound.

InChI:InChI=1/C8H12N2/c1-5-3-7(9)4-6(2)8(5)10/h3-4H,9-10H2,1-2H3

Upstream product

• 618-06-4 m-sulfanilic acid diazonium salt 
• 87-62-7 2,6-dimethylaniline 
• 1023292-40-1 N⁴-(diphenylmethylene)-2,6-dimethylbenzene-1,4-diamine 

Downstream Products

• 102441-52-1 N,N-dibenzoyl-2,6-dimethyl-p-phenylenediamine 
• 1541182-73-3 C₂₆H₃₆N₂O₅ 
• 1541182-84-6 C₃₂H₄₀N₆O₈ 
• 1541182-85-7 C₂₂H₂₄N₆O₄ 
• 1541182-75-5 C₄₅H₅₆N₆O₁₁ 
• 1541182-79-9 C₄₃H₅₂N₆O₁₁ 
• 1541182-80-2 C₄₀H₄₈N₆O₉ 
• 1392273-50-5 tert-butyl 4-amino-3,5-dimethylphenylcarbamate 

Relevant articles and documents

Trans-spanned palladium catalyst for mild and efficient amination of aryl halides with benzophenone imine

A new protocol for palladium-catalyzed Buchwald-Hartwig amination of aryl chlorides and bromides with benzophenone imine as ammonia surrogate is described. The suggested reaction conditions are mild and may therefore be applied to a variety of sensitive starting materials. Georg Thieme Verlag Stuttgart.

Process for dyeing keratinous fibers with aminoindoles and oxidation dye precursors at basic Ph's and dyeing agents

The invention relates to a process for dyeing keratinous fibres, which consists in applying to these fibres a composition containing, in a suitable medium for dyeing, at least one coupler of formula: STR1 where R1 denotes hydrogen or alkyl, R2 and R3 denote hydrogen, alkyl, COOR' where R' is alkyl or hydrogen, at least one of the groups R2 and R3 denoting hydrogen, R4 denotes hydrogen, alkyl, hydroxyalkyl, polyhydroxyalkyl or aminoalkyl, Z1 and Z2 denote hydrogen, alkyl, hydroxyl, halogen, alkoxy, at least one of the groups Z1 and Z2 is other than hydrogen at least one oxidation dye precursor, at least one oxidizing agent, the pH of the composition applied to the fibres being higher than 7.

3-substituted para-aminophenols

The invention concerns the use of a 3-substituted para-aminophenol as an oxidation dye precursor for dyeing keratinous fibres, in particular human hair. The 3-substituted para-aminophenol has formula: STR1 where R1 represents alkyl, alkenyl, mono- or polyhydroxyalkyl, nitrile, cyanoalkyl, halogenoalkyl, aminoalkyl or alkoxyalkyl and R2 represents hydrogen, alkyl or mono- or polyhydroxyalkyl, provided that when R2 is hydrogen R1 is not methyl or trifluoromethyl, and to addition salts thereof with an acid. The invention also concerns dye compositions containing compound (I). The invention further concerns novel 3-substituted para-aminophenols.