72331-54-5Relevant articles and documents
α-Ketocarboxylic acid-based inhibitors of protein tyrosine phosphatases
Chen, Yen Ting,Onaran,Doss, Christopher J.,Seto, Christopher T.
, p. 1935 - 1938 (2007/10/03)
A series of aryl α-ketocarboxylic acids was synthesized and investigated as inhibitors for the protein tyrosine phosphatase from Yersinia enterocolitica. IC50 values for these compounds range from 79 to 2700 μM. Larger aromatic groups, and aromatic groups with high electron density, lead to more potent inhibitors. In general, the related aryl α-hydroxycarboxylic acids show lower activity.
REACTION OF FLUORINATED ARYLMAGNESIUM HALIDES WITH DI-TERT-BUTYL OXALATE
Shadrina, L. P.,Kazakov, A. F.,Dormidontov, Yu. P.,Pirogova, V. V.
, p. 2257 - 2259 (2007/10/02)
The reaction of phenylmagnesium halides fluorinated in the ring or in the side chain with di-tert-butyl oxalate was investigated.It was shown that the esters of arylglyoxalic or arylglycolic acids are formed under various temperature conditions, depending on the electrophilicity of the radical in the organomagnesium compound.
Nuclear Magnetic Resonance Configuration Correlation of Primary Amine Derivatives of α-Methyl-α-methoxy(pentafluorophenyl)acetic Acid
Valente, Edward J.,Pohl, Lance R.,Trager, William F.
, p. 543 - 546 (2007/10/02)
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