72377-05-0 Usage
Description
(S)-2-Ethylhexanoic acid, also known as (S)-2-Ethylhexanoate, is a carboxylic acid with the chemical formula C8H16O2. It is a colorless liquid with a fruity odor and is recognized for its versatility in various industrial applications due to its relatively non-toxic nature and non-hazardous classification.
Uses
Used in Pharmaceutical Industry:
(S)-2-Ethylhexanoic acid is used as a chemical intermediate for the production of various pharmaceuticals. Its role in this industry is crucial as it aids in the synthesis of different medicinal compounds, contributing to the development of new drugs and therapies.
Used in Plasticizer Production:
In the plastics industry, (S)-2-Ethylhexanoic acid serves as a key intermediate in the creation of plasticizers. These are additives that increase the flexibility and workability of plastics, making them more suitable for a wide range of applications, from packaging to construction materials.
Used in Fragrance Industry:
(S)-2-Ethylhexanoic acid is utilized as a precursor in the synthesis of various fragrances. Its fruity odor makes it a valuable component in the development of perfumes, colognes, and other scented products, enhancing the sensory experience for consumers.
Used in Paint and Lubricant Industries:
(S)-2-Ethylhexanoic acid is used as a precursor for the synthesis of metal soaps, which are essential components in the formulation of paint driers and lubricants. These metal soaps help improve the performance and longevity of paints and lubricants, making them more efficient and durable in their respective applications.
Check Digit Verification of cas no
The CAS Registry Mumber 72377-05-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,3,7 and 7 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 72377-05:
(7*7)+(6*2)+(5*3)+(4*7)+(3*7)+(2*0)+(1*5)=130
130 % 10 = 0
So 72377-05-0 is a valid CAS Registry Number.
72377-05-0Relevant articles and documents
Iterative saturation mutagenesis accelerates laboratory evolution of enzyme stereoselectivity: Rigorous comparison with traditional methods
Reetz, Manfred T.,Prasad, Shreenath,Carballeira, Jose D.,Gumulya, Yosephine,Bocola, Marco
experimental part, p. 9144 - 9152 (2010/08/21)
Efficacy in laboratory evolution of enzymes is currently a pressing issue, making comparative studies of different methods and strategies mandatory. Recent reports indicate that iterative saturation mutagenesis (ISM) provides a means to accelerate directed evolution of stereoselectivity and thermostability, but statistically meaningful comparisons with other methods have not been documented to date. In the present study, the efficacy of ISM has been rigorously tested by applying it to the previously most systematically studied enzyme in directed evolution, the lipase from Pseudomonas aeruginosa as a catalyst in the stereoselective hydrolytic kinetic resolution of a chiral ester. Upon screening only 10 000 transformants, unprecedented enantioselectivity was achieved (E = 594). ISM proves to be considerably more efficient than all previous systematic efforts utilizing error-prone polymerase chain reaction at different mutation rates, saturation mutagenesis at hot spots, and/or DNA shuffling, pronounced positive epistatic effects being the underlying reason.
