7250-70-6 Usage
Description
N-(2-Methylphenyl)piperidine, also known as N-Methyl-2-phenylpiperidine, is a chemical compound with the molecular formula C13H17N. It is a piperidine derivative featuring a methylphenyl group attached to the nitrogen atom. N-(2-Methylphenyl)piperidine is recognized for its minimal toxicity, stability under normal conditions, and its role in the synthesis of pharmaceutical compounds, particularly in the development of new drugs for various medical purposes. Additionally, it has been studied for its potential psychoactive effects, although its exact mechanism of action and uses in this area are not fully understood.
Uses
Used in Pharmaceutical Industry:
N-(2-Methylphenyl)piperidine is utilized as a key intermediate in the synthesis of pharmaceutical compounds. Its unique structure allows it to be a valuable building block for the creation of new drugs targeting a range of medical conditions.
Used in Drug Development:
In the field of drug development, N-(2-Methylphenyl)piperidine serves as a crucial component in the formulation of novel therapeutic agents. Its properties make it suitable for the design and synthesis of medications aimed at treating various diseases and disorders.
Used in Research and Development:
N-(2-Methylphenyl)piperidine is also used as a research compound for exploring its potential psychoactive effects. While the exact mechanism of action is not yet fully understood, ongoing studies aim to elucidate its role in this area, potentially leading to new applications in the treatment of neurological or psychiatric conditions.
Overall, N-(2-Methylphenyl)piperidine is a versatile compound with applications spanning across the pharmaceutical industry, drug development, and research, making it an important asset for scientists and researchers in their quest to discover and create new medications and therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 7250-70-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,2,5 and 0 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 7250-70:
(6*7)+(5*2)+(4*5)+(3*0)+(2*7)+(1*0)=86
86 % 10 = 6
So 7250-70-6 is a valid CAS Registry Number.
InChI:InChI=1/C12H17N/c1-11-7-3-4-8-12(11)13-9-5-2-6-10-13/h3-4,7-8H,2,5-6,9-10H2,1H3
7250-70-6Relevant articles and documents
Synthesis of N-heterocyclic carbene-Pd(II)-5-phenyloxazole complexes and initial studies of their catalytic activity toward the Buchwald-Hartwig amination of aryl chlorides
Zhang, Zhi-Mao,Xu, Yu-Ting,Shao, Li-Xiong
, (2021/04/19)
Three new N-heterocyclic carbene (NHC)-Pd(II) complexes using 5-phenyloxazole as the ancillary ligand have been obtained in moderate to good yields by a one-pot reaction of the corresponding imidazolium salts, palladium chloride and 5-phenyloxazole under mild conditions. Initial studies showed that one of the complexes is an efficient catalyst for the Buchwald-Hartwig amination of aryl chlorides with various secondary and primary amines under the varied catalyst loading of 0.01-0.05 mol%, thus it will enrich the chemistry of NHCs and give an alternative catalyst for the coupling of challenging while cost-low aryl chlorides.
Electron Donor-Acceptor Complex-Initiated Photochemical Cyanation for the Preparation of α-Amino Nitriles
Xia, Qing,Li, Yufei,Cheng, Lan,Liang, Xin,Cao, Chenlin,Dai, Peng,Deng, Hongping,Zhang, Weihua,Wang, Qingmin
supporting information, p. 9638 - 9643 (2020/12/21)
An electron donor-acceptor complex-initiated α-cyanation of tertiary amines has been described. The reaction protocol provides a novel method to synthesize various α-amino nitriles under mild conditions. The reaction can proceed smoothly without the presence of photocatalysts and transition metal catalysts, and either oxidants are unnecessary or O2 is the only oxidant. The practicality of this method is showcased not only by the late-stage functionalization of natural alkaloid derivatives and pharmaceutical intermediate, but also by the applicability of a stop-flow microtubing reactor.
N-Heterocyclic carbene-palladacyclic complexes: synthesis, characterization and their applications in the C-N coupling and α-arylation of ketones using aryl chlorides
Liu, Feng,Hu, Yuan-Yuan,Li, Di,Zhou, Quan,Lu, Jian-Mei
, p. 5683 - 5690 (2018/08/24)
N-Heterocyclic carbene-palladacyclic complexes 3 were successfully achieved in a one-pot procedure under mild conditions. The structure of 3a was unambiguously confirmed by X-ray single crystal diffraction and it was an active catalyst in the Buchwald-Hartwig amination and α-arylation of ketones even at very low catalyst loadings (0.01 mol%).
