72560-60-2 Usage
Description
4-Cholesten-3-one-2,2,4,6,6-D5 is a labeled version of Δ4-Cholesten-3-one (C432100(P)), an intestinal metabolite of cholesterol (C432501(P)) with anti-obesity effects on animals. 4-CHOLESTEN-3-ONE-2,2,4,6,6-D5 is utilized in research and development for its potential role in managing obesity and related metabolic disorders.
Uses
Used in Pharmaceutical Research:
4-Cholesten-3-one-2,2,4,6,6-D5 is used as a research compound for studying the metabolic pathways and effects of cholesterol in the body. Its anti-obesity properties make it a valuable tool in the development of treatments for obesity and related metabolic disorders.
Used in Drug Development:
In the pharmaceutical industry, 4-Cholesten-3-one-2,2,4,6,6-D5 is used as a lead compound in the development of new drugs targeting obesity. Its understanding can aid in the creation of medications that modulate cholesterol metabolism and potentially reduce obesity in humans.
Used in Metabolic Studies:
4-Cholesten-3-one-2,2,4,6,6-D5 is utilized in metabolic studies to explore the relationship between cholesterol metabolism and obesity. This can provide insights into the mechanisms behind weight gain and the development of obesity, contributing to a better understanding of these conditions and the creation of effective interventions.
Used in Nutritional Research:
In the field of nutrition, 4-Cholesten-3-one-2,2,4,6,6-D5 is used to investigate the role of cholesterol and its metabolites in weight management. This research can help in formulating dietary recommendations and interventions that may contribute to the prevention and management of obesity.
Check Digit Verification of cas no
The CAS Registry Mumber 72560-60-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,5,6 and 0 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 72560-60:
(7*7)+(6*2)+(5*5)+(4*6)+(3*0)+(2*6)+(1*0)=122
122 % 10 = 2
So 72560-60-2 is a valid CAS Registry Number.
72560-60-2Relevant articles and documents
The synthesis of cholesterol-2,2,4,4,6-d5
Gruenke,Cymerman Craig
, p. 495 - 500,497,498 (1979)
Cholesterol-3,4-d2 and -2,2,4,4,6-d5 have been synthesized from Δ4-cholestene-3-one for use as mass spectrometric stable isotope internal standards. Conversion of Δ4-cholesten-3-one to the enol acetate followed by reduction with sodium borodeuteride in a deuterated solvent yielded cholesterol-3,4-d2. Similarly Δ4-cholesten-3-one-2,2,4,6,6-d5 obtained by base-catalyzed exchange of Δ4-cholesten-3-one in ethanol-0-d1 was converted to the enol acetate, followed by reduction with sodium borohydride in a deuterated medium to give cholesterol-2,2,4,4,6-d5.
