72604-79-6 Usage
General Description
(R)-2-Hydroxymethylbutanoic acid is a chiral compound with a chemical structure consisting of a butanoic acid group and a hydroxymethyl group, both attached to the second carbon of the molecule. (R)-2-Hydroxymethylbutanoic acid is also known as (R)-alpha-hydroxyisobutyric acid and is commonly used in the synthesis of pharmaceuticals and organic compounds. It is a colorless liquid with a faint odor and is soluble in water. It is a valuable building block in organic synthesis due to its ability to form esters and amides, and its chiral nature makes it useful in the production of enantiomerically pure compounds. Additionally, (R)-2-Hydroxymethylbutanoic acid has been studied for its potential use in the treatment of certain metabolic disorders and as a biomarker for various diseases.
Check Digit Verification of cas no
The CAS Registry Mumber 72604-79-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,6,0 and 4 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 72604-79:
(7*7)+(6*2)+(5*6)+(4*0)+(3*4)+(2*7)+(1*9)=126
126 % 10 = 6
So 72604-79-6 is a valid CAS Registry Number.
InChI:InChI=1/C5H10O3/c1-2-4(3-6)5(7)8/h4,6H,2-3H2,1H3,(H,7,8)/t4-/m1/s1
72604-79-6Relevant articles and documents
Synthesis of Enantiomerically Enriched 2-Hydroxymethylalkanoic Acids by Oxidative Desymmetrisation of Achiral 1,3-Diols Mediated by Acetobacter aceti
Brenna, Elisabetta,Cannavale, Flavia,Crotti, Michele,De Vitis, Valerio,Gatti, Francesco G.,Migliazza, Gaia,Molinari, Francesco,Parmeggiani, Fabio,Romano, Diego,Santangelo, Sara
, p. 3796 - 3803 (2016/12/24)
The stereoselective desymmetrisation of achiral 2-alkyl-1,3-diols is performed by oxidation of one of the two enantiotopic primary alcohol moieties by means of Acetobacter aceti MIM 2000/28 to afford the corresponding chiral 2-hydroxymethyl alkanoic acids (up to 94 % ee). The procedure, carried out in aqueous medium under mild conditions of pH, temperature and pressure, contributes to enlarge the portfolio of enzymatic oxidations available to organic chemists for the development of sustainable manufacturing processes.